Postdoc in Modelling of bioproduction from mammalian cells

 

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

Job description

Veronique Chotteau’s group is the Cell Technology group (CETEG) at Dept. Industrial Biotechnology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH. Chotteau has a long experience of developing biopharmaceutical drug bioprocesses for human therapy. CETEG's operations include bioprocessing of perfusion with high cell density, development of dynamic metabolism models and process development for the production of biological drugs, proteins and viral vectors as well as human cells. Chotteau is the Director of the Competence Centre AdBIOPRO for Advanced Bioproduction by Continuous Processing and the Coordinator of the European project iConsensus within the Innovative Medicines Initiative (IMI2). Chotteau is also a partner of the Competence Centre for Advanced Medical Product CAMP and the Marie-Curie EU program project STACCATO.

The Cell Technology group has a vacancy for post-doc in a project Data-Limited Learning of Complex Dynamical Systems, within Digital Futures (https://www.digitalfutures.kth.se), in a collaboration between Assoc. Prof. Veronique Chotteau, Prof. Håkan Hjalmarsson and Assoc. Prof. Saikat Chatterjee. Digital Futures is a multi-disciplinary research centre by KTH, Stockholm University and RISE.

The focus will be on the development of mathematical dynamic models for the production of biological drugs with mammalian or human cells. Models will integrate information from transcriptomics, where machine learning support will be evaluated. Post-doc will develop mathematical dynamic models, e.g. metabolism, glycosylation, based on existing experimental data from CETEG, and will perform new experiments for modelling purposes. The study will be carried out in collaboration with teams from System Identification (Prof. Håkan Hjalmarsson, Division of Decision and Control Systems, KTH) and Machine Learning (Assoc. Prof. Saikat Chatterjee, Dept of Information Science and Engineering, KTH). The practical work will take place at KTH, AlbaNova University Center, Stockholm.

What we offer

• A position at a leading technical university that generates knowledge and skills for a sustainable future
• Engaged and ambitious colleagues along with a creative, international and dynamic working environment
• Works in Stockholm, in close proximity to nature
• Help to relocate and be settled in Sweden and at KTH

Read more about what it is like to work at KTH

Qualifications

Requirements

• A doctoral degree in Engineering or an equivalent foreign degree in in biotechnology, bioprocess technology, control technology or bioinformatics, obtained within the last three years prior to the application deadline (With some exceptions for special reasons such as periods of sick or parental leave, kindly indicate if such reason exists in your resume).
• As a person you have the ability for work independently and drive your work in collaboration with supervisors and researchers.
• The candidate we are looking for must have a high technical ability and laboratory experience.
• The candidate should have a high flexibility and very good collaboration-, problem solving- and critical analytical ability.
• The candidate should have excellent communication skills in scientific English, both orally and in writing.

Preferred qualifications

• Knowledge and experience of mathematical modelling, bioinformatics and mammalian cell culture bioprocess are strong merits.
• Applicants must be strongly motivated for postgraduate studies.
• Awareness of diversity and equal opportunity issues, with specific focus on gender equality.

Great emphasis will be placed on personal competency.

Trade union representatives

You will find contact information to trade union representatives at KTH's webbpage.

Application

Log into KTH's recruitment system in order to apply to this position. You are the main responsible to ensure that your application is complete according to the ad.

The application must include:

• CV including relevant professional experience and knowledge.
• Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents have not been issued in any of these languages.
• Brief account of why you want to conduct research, your academic interests and how they relate to your previous studies and future goals. Max two pages long.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The position offered is for, at the most, two years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Others

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

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