The Max Planck Institute for Multidisciplinary Sciences is a leading international research institute of exceptional scientific breadth. With more than 40 research groups and some 1,000 employees from over 50 nations, it is the largest institute of the Max Planck Society.
The research group of Molecular Mechanisms of Membrane Trafficking (Dr. Oleksiy Kovtun) at the City-Campus invites applications for a position as a PhD student (f/m/d) - Structural studies of endosomal complexes guiding membrane trafficking.
The organised flow of membrane-encapsulated molecular cargo plays a key role in cell homeostasis and adaptation. Endosomes serve as hubs of this membrane trafficking, directing different cargo types to their specific destinations. Dedicated molecular machines guide cargoes to various sorting routes however, details of this process are elusive. We aim to understand the mechanisms of endosomal trafficking through structural studies of sorting complexes on membranes complemented by biochemical and functional analysis.
We offer up to two fully-funded PhD positions to explore the structural basis of membrane trafficking on endosomes. Cryo-election microscopy and tomography augmented with comprehensive image processing will make the core research approach. In addition, the projects will utilise general wet lab techniques (cloning, recombinant proteins production, cell culture handling, etc.), interaction analysis and molecular modelling. For research example see PMID 30224749 and 33762348.
Your profile
- hold (or soon to be conferred) Master’s or equivalent degree in Biochemistry, Biophysics, Bioinformatics or related discipline.
- proficient written and spoken English.
- strong background in at least one of the following: biochemistry, cell biology, structure biology, digital data processing.
- experience in structural biology, electron microscopy, digital image processing and programming would be beneficial.
- keen interest in solving life science problems through self-driven research.
What we offer
- Interesting and varied work in an interdisciplinary environment
- A wide range of offers to help you balance work and family life: on-campus kindergarten places including vacation care, parent-child offices, etc.
- Further training opportunities and language courses
- Spacious cafeteria with a wide range of meals plus an espresso bar
- Health management: free fitness and yoga room, sports groups, course offerings for a "moving break"
- Initiatives for sustainability and a green environment with a new biotope
About us
We are a newly established group based in the City Campus of the Institute for Multidisciplinary Sciences, the largest institute of Max Plank Society. The institute's and broader Göttingen research community provide an excellent networking and collaborating environment. Our research is facilitated by modern laboratory and office space and access to word-class instrumentation, including high-end EM facility and supercomputing resources.
Position details
The position should be filled as soon as possible; the exact start date is flexible. Payment and benefits are based on the German public service pay scale (TVöD Bund) guidelines. Successful candidates will be able to join a PhD program, with three years funding, within Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences, a collaboration with the University of Göttingen.
The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds.
Application
Applications will be accepted until positions are filled. Informal inquiries are welcome and should be directed to Dr. Kovtun oleksiy.kovtun@mpinat.mpg.de.
Please submit your application, including cover letter (explaining background and motivation), CV, transcripts, list of publications, and the contact details of at least two academic referees preferably by e-mail as a single PDF file to:
ausschreibung07-22@mpinat.mpg.de
Max Planck Institute for Multidisciplinary Sciences
Research Group of Molecular Mechanisms of Membrane Trafficking
Dr. Oleksiy Kovtun
Hermann-Rein-Straße 3
37075 Göttingen
Germany
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