The Department of Biomedicine, Faculty of Health, Aarhus University invites applications for a position as Postdoc in the field of infection biology and neuroscience as per 1 August 2022 or as soon as possible thereafter. The position is a 3 year full-time position.
As a person, you are ambitious, take ownership and possess good communication and interpersonal skills. We expect you to be fluent in oral and written English. In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.
Shortlisting will be used.
We expect to conduct interviews the third weeks of May.
About the research project
Virus infections in the brain can cause acute disease (encephalitis) and prime for longterm pathologies (e.g. neurodegenerative diseases). Therefore, the brain needs to have efficient antiviral mechanisms in place to restrict virus replication. Currently, there is limited knowledge on how neurons and glial cells control virus infections without activating inflammatory activities, which can also cause pathology. To identify novel mechanisms of cell-autonomous antiviral activity in neurons, we will use genome-wide CRISPR screens and neuron cell models. Focus will be on neurotropic herpesviruses. Identified candidates will be mechanistically characterized, and experimentally tested in mice and organoid systems.Your job responsibilities
As Postdoc in infection biology and neuroscience your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance. The work related to the project will take place at Department of Biomedicine. Your main tasks will consist of: Independent research of high international quality, including publication.Your competences
You have academic qualifications at the PhD level, preferably within one or more of the following areas virology, immunology, or neuroscience. Previous documented experience with genome-wide screens or CRISPR/Cas9 technology is an advantage. Experience with culture of neurons and/or animal models for brain diseases is also seen as an advantage. You should have solid analytical thinking, creativity, and a visible publication record. We offer a dynamic, ambitious, and productive environment for a young scientist, and a good platform for a future career in frontline research. You will report to Professor Søren Riis Paludan.The department
We offer a vibrant international research environment where English is the preferred language in the laboratory, at meetings and at seminars. The Department employs some 450 people and covers a range of research areas within Biomedicine. We contribute to the Bachelor’s degree programs in medicine, molecular medicine, odontology and the Master’s degree programs in biomedical engineering and medical chemistry. Our infrastructure is well developed with modern laboratories, core and animal facilities. You will work in the ‘Skou Building’ located at the heart of the university campus. You can read more about the department here and about the faculty here.Recent publications from the project group:
- Reinert et al. Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production. Journal of Clinical Investigation. 2021. 131(1):e136824:
- Paludan, et al. Constitutive immune mechanisms: mediators of host defence and immune regulation. Nature Reviews Immunology. 2021. 21:137-150.
- Katzilieris-Petras G et al. Microglia activate early anti-viral responses upon HSV-1 entry into the brain to counteract development of encephalitis-like disease in mice. Journal of Virology. 2022. Epub ahead of print.
As a person, you are ambitious, take ownership and possess good communication and interpersonal skills. We expect you to be fluent in oral and written English. In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.
Shortlisting will be used.
Questions about the position
If you have any questions about the position, please contact Professor Søren Riis Paludan tel.: (+45) 28992066; email: srp@biomed.au.dk.We expect to conduct interviews the third weeks of May.
Terms of employment
Application
Your application must include the following:We refer to the faculty’s Guidelines for applicants.
The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.
Letter of reference
If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.
International applicant?
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
Deadline15 Apr
Expected start1 Aug
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