Applicants are invited for a 3 year position as Postdoctoral Fellow in Physiology to be based at Institute for Basic Medical Science (IMB), the Department of Molecular medicine, Section for Physiology, University of Oslo.
The position is connected to the convergence environment 3DR with the main aim of increasing the availability and function of donor organs. This interdisciplinary team consists of scientists from biology, basic and clinical medicine and theology. The announced position is connected to the heart physiology group at IMB. More information about the group can be found here: https://www.med.uio.no/imb/english/research/groups/heart-physiology/index.html
More about the position
The main purpose of the fellowship is to qualify researchers for work in higher academic positions within their disciplines. The main aim for the announced position is establish and test methods to evaluate cardiac function in donor heart after circulatory death in experimental rodent models. The hearts will be exposed to at least 5 minutes of warm ischemia and will thereafter be perfused ex vivo in isolated perfusion systems (either Langendorff or working heart). Different cardioplegic and cardio preservation solutions will be tested. Cardiac performance and molecular analysis will be tested on hearts ex vivo and in vitro. One target is reduced mitochondrial damage during reperfusion. In later parts of the project, the best strategies can also be tested with in vivo ischemia reperfusion models in rodents. Noninvasive ultrasound will be used to evaluate cardiac function.
The successful candidate will be a person with relevant background and the ability to work both in team and independently. Experience with independent project management, supervision and interest in interdisciplinary projects is an advantage. Practical experience with animal handling and cardiovascular experiments is an absolute requirement.
Qualification requirements
Requirements:
Applicants must hold a degree equivalent to a Norwegian doctoral degree within cardiovascular physiology/cardiology. Doctoral dissertation must be submitted for evaluation by the closing date. Appointment is dependent on the public defense of the doctoral thesis being approved.
FELASA C (Animal handling course)
Experience with handling rodents
Fluent oral and written communication skills in English (and or Scandinavian).
The following qualifications will count strongly in the assessment of the applicants:
Experience with isolated perfused rodent hearts
Experience with ultrasound Doppler in rodent models of cardiac disease
Experience with general molecular techniques (histology, western blot, qPCR)
Some experience in supervision of students
Personal suitability
Administrative experience
Other qualifications
Knowledge in mitochondrial biology
Knowledge in metabolism
Experience with primary isolated cardiac cell or cell lines
Personal skills
The ability to work in team and independently
Well organized and solution oriented
Able to interact with scientist from different disciplines
We offer
Salary NOK 534 400 – 615 800 per annum depending on qualifications in position as Postdoctoral Research Fellow (position code 1352)
A professionally stimulating working environment
Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
How to apply
The application must include
Cover letter (statement of motivation, summarizing scientific work and research interest)
CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
Copies of educational certificates (academic transcripts only)
FELASA C documentation
A complete list of publications
List of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)
The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).
In assessing the applications, special emphasis will be placed on the documented, academic qualifications, the project description (whenever this is required in the call for applicants), and the quality of the project as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.
It is expected that the successful candidate will be able to complete the project in the course of the period of employment.
Formal regulations
Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.
No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.
According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.
The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.
The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.
Contact information
Professor: Kåre-Olav Stensløkken, phone number: +47 97690730, e-mail: k.o.stenslokken@medisin.uio.no
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About the University of Oslo
The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.
The Institute of Basic Medical Sciences overall objective is to promote basic medical knowledge in order to understand normal processes, provide insight into mechanisms that cause illness, and promote good health. The Institute is responsible for teaching in basic medical sciences for the programmes of professional study in medicine and the Master's programme in clinical nutrition. The Institute has more than 300 employees and is located in Domus Medica.
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