Postdoctoral Research Fellow in modelling of organoid/gastruloid morphogenesis

 


A three-year Postdoctoral Research Fellowship is available at The Njord Centre. The purpose of the possition is to develop a theoretical understanding and computational models of development principles in organoid/gastruloid morphogenesis.


No one can be appointed for more than one Postdoctoral Research Fellowship at the University of Oslo.


Starting date as soon as possible.


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More about the position

About the project:


The position is part of the UiO: Life Science convergence environment “Integrated technologies for tracking organoid/gastruloid morphogenesis” (ITOM). Embryonic stem cell (ESC) technology has allowed the development of organoids/gastruloids that show features of organ induction but lack further maturation and show large variations. The field, therefore, requires high-content tracking tools and algorithms to guide organoid/gastruloid development. The project will use advanced correlative imaging technologies and data analysis to guide the differentiation of ESC-derived organoids/gastruloids. The ITOM project unites three different Centres of Excellence in the Oslo area: HTH-CoE, Njord-CoE, and RITMO-CoE. As such, the candidate will be part of a large and closely interacting interdisciplinary team of basic scientists, developmental biologists, chemists, physicists, computational scientists, and rhythm researchers.


Job description:


The recruited postdoctoral fellow will develop physics-based computational models of morphogenesis using the experimental observations from tracking and guiding organoid/gastruloid development. We aim to create computer simulations of the organoid growth and to better understand the key self-organization principles of cells and their collective response to external perturbations during organoid/gastruloid formation. This is an interdisciplinary project that will integrate the experimental observations and data analysis including machine learning methods. 


The candidate will be supervised by Prof. Luiza Angheluta from Njord Centre/Department of Physics, where the candidate will be hosted. Co-supervision will be provided by Prof. Dag Kristian Dysthe (Njord Centre) and Prof. Stefan Krauss (HTH Centre). We expect that the candidate will work closely with three other early career researchers recruited to the other ITOM projects and be an active part of the collaboration with the team at  Hybrid Technology Hub (HTH) and the team at RITMO.


The main purpose of a postdoctoral fellowship is to provide the candidates with enhanced skills to pursue a scientific top position within or beyond academia. To promote a strategic career path, all postdoctoral research fellows are required to submit a professional development plan no later than one month after commencement of the postdoctoral period.


About condensed matter and biophysics at the Njord Centre:


The project is carried out at the Njord Centre located in the Condensed matter physics section at the Department of Physics, University of Oslo. The successful candidate will benefit from an open, diverse, and interdisciplinary research environment at the Njord Centre. The postdoctoral fellow will contribute to strengthen our biological soft matter group and our aim is to also integrate it with other research initiatives at Njord Centre.


Qualification requirements

The Faculty of Mathematics and Natural Sciences has a strategic ambition is to be among Europe’s leading communities for research, education and innovation. Candidates for these fellowships will be selected in accordance with this, and expected to be in the upper segment of their class with respect to academic credentials.


Required qualifications


Applicants must hold a degree equivalent to a Norwegian doctoral degree in physics or applied mathematics. Doctoral dissertation must be submitted for evaluation by the closing date. Only applicants with an approved doctoral thesis and public defence are eligible for appointment.

Strong programming skills

Experience in modelling of biological matter and in related fields: computational physics, statistical soft matter physics, biophysics and mathematical/theoretical biology

Fluent oral and written communication skills in English

Personal suitability and motivation for the position.

In the evaluation of the applications, emphasis will be placed on:


The applicant’s academic qualifications.

The research statement.

The applicant’s estimated academic and personal ability to carry out the project within the allotted time frame and contribute to the research objectives of ITOM.

Collaboration skills and the ability to successfully join in academic teamwork within and across disciplines.

We offer

Salary NOK 534 400 – 594 300 per annum depending on qualifications in position as Postdoctoral Research Fellowship (position code 1352)

Attractive welfare benefits and a generous pension agreement

Professionally stimulating working environment

Vibrant international academic environment

Postdoctoral development programmes

Oslo’s family-friendly surroundings with their rich opportunities for culture and outdoor activities

How to apply

The application must include


Cover letter including a research statement giving the motivation and research interests in the project

CV (summarizing education, positions and academic work).

Copies of educational certificates (academic transcripts only).

A complete list of publications and academic works.

List of at least two reference persons (name, relation to candidate, e-mail and phone number).

Letters of recommendation (optional).                                                                     

The application with attachments must be delivered in our electronic recruiting system, please follow the link “apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).


Interviews with the best qualified candidates will be arranged.


Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.


According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.


If an applicant has applied for and been granted funding for a research stay abroad while being employed as a Postdoctoral Research Fellow, the employment will be prolonged with the equivalent time as the research stay, but for no longer than twelve months (thus extending the employment to a maximum of four years).


The University of Oslo has an agreement for all employees, aiming to secure rights to research results a.o.


The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.


Contact information

Prof. Luiza Angheluta, e-mail: luiza.angheluta@fys.uio.no


For questions regarding the recruitment system, please contact HR Adviser Elin Thoresen, e-mail: elin.thoresen@mn.uio.no


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About the University of Oslo 

The University of Oslo is Norway’s oldest and highest rated institution of research and education with 28 000 students and 7000 employees. Its broad range of academic disciplines and internationally esteemed research communities make UiO an important contributor to society. 


Njord is a cross-disciplinary Geology-Physics center hosted by the Faculty of Mathematics and Natural Sciences at the University of Oslo. We focus on the fundamental physics of geological processes related to: transport and reactions in deformable porous media, fracturing and fragmentation processes, interface dynamics during geophysical flows, and intermittency and pattern formation in geological systems far from equilibrium.


We conduct research on earth systems that range in scale from atoms to continents and apply methods where fieldwork, numerical modelling, experiments and theory act in concert.


The center includes the Oslo-branch of PoreLab, which is a Center of Excellence (CoE), the former CoE, Physics of Geological Processes (PGP) and several externally financed projects. There are 10 professors and associate professors at the center, in addition to doctoral research fellows, postdoctoral fellows, researchers and technical and administrative staff - in total about 55 persons.


 


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