Friday, July 23, 2021

PhD scholarship in Clinical Radiation Oncology

 

DTU Health Tech, Technical University of Denmark and Rigshospitalet, Department of Oncology is seeking a candidate for a PhD position to develop individualized risk-based radiotherapy dose optimization. The successful candidate will join a multidisciplinary team of supervisors (physicists and medical doctors) from the two institutions.

A multidisciplinary research group focuses on developing next generation of treatments on the high technology platform in close collaboration with the clinical team. Two professors in radiation oncology (Lena Specht, MD and physicist Ivan Vogelius) will be part of the team of supervisors for the PhD project.

Responsibilities and qualifications
The goal of the PhD is to develop risk-based dose planning using high-performance computing following the proofs of concepts published in 1,2 but implemented in commercial treatment planning systems using, for example, scripting application programming interface. We hypothesize that it is possible to automatically generate a large number of deliverable radiation dose plans that in combination span the space of realistic clinical compromises. Thus, the aim is to provide the treating physician with a solution space of deliverable radiation dose distributions from which a comprehensive risk assessment procedure should provide decision support on choice of dose delivery taking the risks of long-term adverse effect into account.

The PhD is funded by the Danish Cancer Society and DTU Health in combination.

You must have a two-year master's degree (120 ECTS points) or an equivalent degree in engineering or physics with an interest in radiation physics and medical applications of ionizing radiation.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

We offer
We offer an exciting and challenging job in an international academic environment with excellent possibilities for professional and personal development. The successful candidate will work in a cross-disciplinary and cross institutional environment with high ambitions to use technological innovations to improve patient care. 

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. The period of employment is 3 years.


The place of work is DTU Health Tech and Rigshospitalet.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Ivan Vogelius (ivan.richter.vogelius@regionh.dk, +45 3545 9885) or Jonas Henriksen (jhen@dtu.dk - +45 4058 2866) 


If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 30 August 2021 (Danish time)Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Health tech
DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 130 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Rigshospitalet, Department of Oncology
Section of radiotherapy within the department of oncology employs 130 people and provide more than 40,000 radiotherapy treatments annually to some 4,300 patients. The department is equipped with state-of-the-art linear accelerators from Varian Medical Systems and a combined MR accelerator from Viewray. In addition, we have two CT scanners, MR scanner, brachytherapy etc. for a total value of equipment exceeding 400 mio DKK.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.


References

  1. Rechner LA, Modiri A, Stick LB, et al. Biological optimization for mediastinal lymphoma radiotherapy - a preliminary study. Acta Oncol. 2020;59(8):879-887.
  2. Stick LB, Vogelius IR, Modiri A, et al. Inverse radiotherapy planning based on bioeffect modelling for locally advanced left-sided breast cancer. Radiother Oncol. 2019;136:9-14.

Apply for this job

Apply no later than 30 August 2021
Apply for the job at DTU Health Tech by completing the following form.

Apply online

Postdoc in Nano-Optoelectronics

 


At the Technical University of Denmark (DTU), we recently established a new research center, NanoPhoton – Center for Nanophotonics (https://nanophoton.dtu.dk/), to perform fundamental and applied research on a newly discovered class of semiconductor nanostructures, termed dielectric bowtie cavities. These cavities confine light to spots in the nanometer range and open several new and previously unimagined possibilities within quantum and information technology.

In this project, we want to explore the bowtie cavity concept to address one of the most important and yet unsolved challenges in information technology, namely how to integrate photonics and electronics. Solving that problem could lead to a considerable speed-up of computers and interconnects and significant energy savings. However, progress is required in several research disciplines, including light-matter interaction in nanostructures, nanofabrication, nanoscale material characterisation, and modelling and design. NanoPhoton is enabled by a major center grant from the Danish National Research Foundation and gathers leading experts within all these disciplines from several Departments at DTU.  

Responsibilities and tasks
The postdoc will be responsible for analysing the fundamental properties of nanolasers and nanophotodetectors integrated with transistors. This includes establishing physical models for the devices and the interface and subsequent analysis using computer simulations and analytical techniques. Based on the insight obtained, the candidate will guide the design of actual structures to be fabricated in DTU's cleanroom. Depending on interest and background, the candidate may also contribute to the experimental characterisation of the fabricated devices.  

Qualifications
Candidates should have a PhD degree in physics or electrical engineering. In the selection of candidates, special consideration will be given to:

  • Expertise in nanoelectronics or nanophotonics
  • Expertise in mathematical modelling and analysis of physical systems
  • Experience in experimental characterisation of photonic or electrical devices
  • A strong drive, interest in acquiring new skills, and a strong team spirit
  • Good communication skills, including a track-record of publications in high-level journals within relevant fields
  • Interest in the supervision of students

We offer
DTU is a leading technical university globally recognised for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterised by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. 

The period of employment is two years. The preferred starting date is 1 November 2021, or as soon as possible after that.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Professor Jesper Mørk, tel.: +45 2082 4576, email: jesm@dtu.dk or Professor Kresten Yvind, email: kryv@dtu.dk

You can read more about DTU Fotonik at www.fotonik.dtu.dk/english.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.  

Application procedure
Your complete online application must be submitted no later than 30 August 2021 (Danish time)Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • List of reference persons
  • Diploma (MSc/PhD)
  • List of publications

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Fotonik has 220 employees and is one of the largest research centers in the world focusing entirely on photonics. Research is performed within the span from fundamental science to applications, emphasising the areas of nanophotonics, lasers, quantum photonics, optical sensors, LEDs, photovoltaics, ultra-high speed optical transmission systems, and bio-photonics.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Apply for this job

Apply no later than 30 August 2021
Apply for the job at DTU Fotonik by completing the following form.

Apply online

PhD scholarship in AI Methods for Improving Process Safety in Automation Systems

 


DTU Electrical Engineering seeks qualified and talented candidates for a vacant PhD position in Improving Process Safety by Applying Model-based Methods.

The purpose of the project is to define function modelling framework and implement model-based AI reasoning solutions, i.e. to develop representations and algorithms, to support a variety of industrial safety assessment procedures including Hazard Identification and Risk Assessment. The model-based reasoning system will be applied for knowledge management and decision support to facilitate the industrial safety assessment activities.  

Your work will have the potential to influence the current industrial practices, and subsequently improve the safety and reliability of industrial systems, reducing the social and environmental impact due to industrial accidents.

Responsibilities and qualifications
Safety Assessment is a key building block through industrial plants’ life cycle, which includes important steps such as hazard identification and afterwards risk evaluation. The result of it subsequently is used to support decision making during plant design, operation and maintenance, to eliminate or mitigate risks and improve safety level of the systems. However, many results of the safety assessment activities such as HAZOP studies are highly dependent on human experience and they are unlikely to be complete, consistent and error-free.   


Model-based methods are gaining recognitions in Safety Assessment due to their features such as concrete knowledge representations and consistent knowledge-based reasoning. These features bring great potential to improve the efficiency of the Safety Assessment procedure and consistency of its result. The models developed for such a purpose should represent the safety objectives and functions explicitly and always be maintained and updated, corresponding to new operational situations and changing operational conditions to support Safety Assessment through the plants’ life cycle.   

The overall aim of the project is to define formal knowledge representation and develop reasoning algorithms for Safety Assessment methods based on one of the functional modelling approach called Multilevel Flow Modelling (MFM). Current research in MFM at DTU Electrical Engineering is about developing MFM based reasoning algorithms and software tools for the analysis of causes and consequences of disturbances in industrial plants like oil and gas production plants. More information regarding MFM can be found at https://www.mfm.elektro.dtu.dk/, and additional training will be provided once the project starts. The methodology will be applicable to all kinds of complex process facilities, power plants, infrastructure and more.

The project is part of a research program “operations and maintenance technology” funded by the Danish Hydrocarbon Research and Technology Center (DHRTC). The overall purpose of the program is to improve operations and safety of oil and gas production platforms in the Danish North Sea. MFM here plays a central role as a methodology for representation of plant knowledge and for Safety Assessment, Operation Support and Maintenance Planning. MFM is the technology basis for the Control Room Assistant (CRA), software developed by the project partner Kairos Technology, and will be applied again to a new software product called the “Hazop Assistant”.

We are searching for applicants that with one (or more) of the following background:

  • General Automation or Process control
  • Safety Engineering
  • Artificial Intelligence (rule based systems and knowledge representation)

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.  

Assessment
The assessment of the applicants will be made by Professor Ole Ravn and Assistant Professor Xinxin Zhang, DTU Electrical Engineering and Jørgen Rentler Næumann, DHRTC DTU.  

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.


Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. 

The starting date is 1 November 2021.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Assistant Professor Xinxin Zhang, xinz@elektro.dtu.dk

You can read more about DTU Electrical Engineering at www.elektro.dtu.dk, and about “DHRTC” at www.oilgas.dtu.dk/english.   

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.  

Application procedure
Your complete online application must be submitted no later than 29 August 2021 (Danish time)Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.  

The Automation and Control group performs research and teaching in automation technology, control theory, robotics and autonomous systems at DTU. The group has 54 affiliated researchers and other employees. Please read more about the Automation and Control group on www.aut.elektro.dtu.dk/.  

DTU Electrical Engineering educates students within electrical engineering technologies. We offer studies at BEng, BSc, MSc, and PhD levels, and participate in joint international programmes. We conduct excellent research within acoustic technologies, electromagnetic systems, electronics, autonomous systems, robotic technologies, digital energy solutions, interconnected energy systems, electric energy technologies, and not least electrification in many respects. Our Department has more than 200 members of staff.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world

Apply for this job

Apply no later than 29 August 2021
Apply for the job at DTU Electrical Eng by completing the following form.

Apply online

Postdoc in Enzyme Discovery

 


Postdoctoral fellows are encouraged to apply for a position at Department of Biotechnology and Biomedicine (DTU Bioengineering) at the Technical University of Denmark placed in the Enzyme and Protein Chemistry group in the section of Protein Chemistry and Enzyme Technology with about 80 staff members. The employment depends on applicant’s expertise and can be for 24 months.

The work is part of a project ‘DSMADE’ (Discovery, Specificity and Mechanism of Alginate Degrading Enzymes) granted by the Independent Research Fund Denmark ! Natural Sciences.

The research will be carried out at DTU Bioengineering, DTU Compute, DTU Biosustain, Norwegian University of Science and Technology (NTNU), University of Barcelona and University of Aix-Marseille involving Bernard Henrissat, Ole Winther, Casper Wilkens, Ditte H. Welner, Carme Rovira, Finn L. Aachmann and Birte Svensson. 

Responsibilities and qualifications
Initial focus is on applying bioinformatics and developing deep learning tools to identify candidates primarily of alginate lyases in a wide range of polysaccharide lyase families by exploring biological sequence databases, gene catalogues and bacterial genomes. Identified candidates are then subjected to validation of the predictive tools by determination of three-dimensional structures and biochemical and enzymatic characterization after recombinant production. Further, selected three-dimensional structures of enzyme-oligosaccharide complexes will be subjected to computational analysis of the mechanism of action. Alginate is a marine polysaccharide composed of mannuronate and guluronate residues organized in different block structures. We aim at identifying tools for disclosing the relationship between the fine substrate specificity and the reactions at the activity sites of these diversely evolved enzymes. Additionally we shall investigate structure/function relationships of the enzyme candidates and the synergism between exo-and endo-acting enzymes with different substrate preferences using defined alginates and polyuronic acids as substrates.   


The successful candidate will benefit from being part of a multidisciplinary project advancing validated accurate annotation of the function of polyuronic acid degrading enzymes. The partners provide excellent collaborating research environments including state-of-the-art computations and data science, infrastructure and instrumentation. Alongside the DSMADE project related experimental research is pursued on alginate converting enzymes by several of the different partners. In particular at DTU Bioengineering and NTNU a number of other young scientists work on alginate converting enzymes mostly on biochemical, structural and enzymatic properties. 

Finally, even though DSMADE has no formal industrial partner we are well connected with industries working on production of alginates and oligosaccharides derived thereof for various applications in the food and pharma sectors.  

As a formal qualification, you must hold a PhD degree (or equivalent) earned no more than 4 years before the deadline for application to this advertisement.

We expect you have a solid background within bioinformatics and protein science and a good understanding of protein and enzyme structure-function relationships.

Experience with several of the below topics will be a special advantage:

  • Machine learning
  • X-ray crystallography
  • Molecular dynamics
  • CAZymes
  • Carbohydrate chemistry including on polyuronic acids
  • Enzyme mechanisms

We expect you are motivated for:

  • individual as well as team accomplishments
  • working in a multidisciplinary project
  • interacting with international research leaders and their research groups

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The position will be available from 1 October 2021 or soon thereafter.

The workplace will be at departments located on the DTU main campus in Lyngby, 10 km north of Copenhagen in Denmark with work visits to partners in Trondheim, Barcelona and Marseille. 

You can read more about career paths at DTU here

Further information
Further information may be obtained from Professor Birte Svensson (tel.: +45 4525 2740; bis@bio.dtu.dk), Assistant Professor Casper Wilkens (cwil@dtu.dk) and Professor Bernard Henrissat (behen@dtu.dk) all at DTU Bioengineering. 


You can read more about DTU Bioengineering on www.bioengineering.dtu.dk.  

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark

Application procedure
Your complete online application must be submitted no later than 27 August 2021 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD)
  • List of publications
  • Up to three letters of recommendation

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science industry and point towards innovation, new businesses and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 220 employees, of which 2/3 is scientific staff. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Apply for this job

Apply no later than 27 August 2021
Apply for the job at DTU Bioengineering by completing the following form.

Apply online