Showing posts with label PhD. Show all posts
Showing posts with label PhD. Show all posts

PhD researcher at the Amsterdam School of Historical Studies

 


The Amsterdam School of Historical Studies (ASH) currently has a vacant PhD position as part of the NWO-funded VIDI Project The Female Impact. Women, the Art Market and Household Consumption in the Dutch Republic, 1580-1720, led by Principal investigator (PI) Judith Noorman. ASH is one of the six research schools under the aegis of the Amsterdam Institute for Humanities Research.

What are you going to do

This PhD project is one of three closely-related projects, which together aim to map, measure and analyse the impact of women on the Dutch art market in the (long) seventeenth century by studying the household as an economic site. Funded through a VIDI-grant of the Netherlands Organization for Scientific Research (NWO), the programme takes an interdisciplinary approach to study women in the art market via three inter-related avenues:

  1. to collect and analyse diverse archival documents bearing witness to women’s household possessions and purchasing power;
  2. to study women’s tastes and preferences as consumers;
  3. to study the household as a space of consumption within which women found employment relating to the art market.

The PhD researcher will study objective 3 by providing an overview of women’s professional participation in the art market of the seventeenth-century Dutch Republic. Aside from women artists, the PhD candidate will study shop keepers, appraisers, art dealers and women in other professional roles to assess how various women navigated the art market, how many succeeded, and how they could be productive. The successful applicant will work closely with the postdoctoral researcher and the PI. A detailed research outline on the project may be obtained from Judith Noorman.

Tasks of the PhD candidate will include:

  • submission of a PhD thesis within the period of appointment;
  • participating in meetings of the project research group and developing a shared database;
  • publishing one single-authored, peer reviewed article;
  • presenting intermediate research results at workshops and conferences;
  • organizing knowledge dissemination activities;
  • co-organizing an international conference on women's impact on the early modern art market;
  • participation in the ASH and Faculty of Humanities PhD training programs.

What do we require

As successful applicant you must have:

  • a completed Master's degree History or Art History, preferably of the early modern period. You may apply if you have not yet completed your Master's degree only if you provide a signed letter from your supervisor stating that you will graduate before 1 September 2021;
  • excellent research skills demonstrated by an outstanding Master's thesis and a demonstrable capacity to develop a track record of publishing in high-ranking journals and/or with leading presses;
  • a strong cooperative attitude and willingness to engage in collaborative research;
  • enthusiasm for communicating academic research to non-academic audiences;
  • excellent command of Dutch and English.

Please note: if you already hold a doctorate/PhD or are working towards obtaining a similar degree elsewhere, you will not be admitted to a doctoral programme at the UvA.

Our offer

You will be employed at the University of Amsterdam’s Faculty of Humanities within the Amsterdam School of Historical Studies (ASH).

The employment contract will be for 48 months, full-time (38 hours per week), under the terms of employment currently valid for the Faculty. The first contract will be for 16 months, with an extension for the following 32 months, contingent on a positive performance evaluation within the first 12 months. The intended starting date is 1 September 2021.

The gross monthly salary will be €2,395 during the first year to reach €3,061 during the fourth year, based on 38 hours per week, in accordance with the Collective Labour Agreement of Dutch Universities.

As PhD candidate you receive a tuition fee waiver and have free access to courses offered by the Graduate School of the Faculty of Humanities and the Dutch National Research Schools.

Questions

For further information, please contact:

About the Faculty of Humanities and the Amsterdam School of Historical Studies

The Faculty of Humanities offers a range of BA and MA programmes with a strong international profile and a large number of disciplines in the field of language and culture. Its research covers all important subdisciplines of the Humanities.

ASH is one of the six research schools/institutes under the aegis of the Amsterdam Institute for Humanities Research. Each research school/institute covers an important research area within the faculty and has its own research programme. Research schools/institute are also the home base for PhD candidates, who interact with each other and with senior members in the research groups that make up the research school.

Job application

The UvA is an equal-opportunity employer. We prioritise diversity and are committed to creating an inclusive environment for everyone. We value a spirit of enquiry and perseverance, provide the space to keep asking questions, and promote a culture of curiosity and creativity.

Applications should include the following information, in a single PDF file (not zipped):

  • a letter of motivation;
  • a research proposal of 800-1000 words, showing how the candidate would approach the project;
  • a full academic CV;
  • a list of all Master-level modules you have taken, with an official transcript of grades;
  • the names and contact details of two referees who may be approached by the selection committee.

Please submit your application by means of the link below (use the obliged field ‘CV’ in the application form) no later than 26 April 2021.

Only complete applications submitted as one PDF file will be considered.

Interviews will probably take place between 17 - 20 May 2021. All interviews will be held via Zoom.



PhD position in characterization and quantitation of nanoplastics in environmental samples

 


The  Van ‘t Hoff Institute for Molecular Sciences is looking for a PhD candidate for the characterization and quantitation of nanoplastics in environmental samples.

In recent years, the scientific focus has shifted from analysing visible plastic particles to detecting microscopic plastic particles, typically using spectroscopic (microscopy‐FTIR or ‐Raman) or thermal degradation analyses (e.g.pyr‐GCMS). Up to now, the efforts have been focused most often on particle sizes above 1 μm. The analytical complexity to identify and monitor nano/microplastics (NMPs) in environmental matrices, increases with decreasing size. This explains why attention has mostly focused on particle sizes much above the 1 μm size range. As a consequence, there is still no consensus regarding methodology for sampling and identifying plastic particles in the nanometric range in complex aqueous matrices, nor are there yet environmental occurrence data available for nanoplastics. This lack of consensus is also caused by the fact that different groups have been investigating and proposing different methods with different size thresholds, which hinders comparison between results and, ultimately, limits progress in this field.

The main goal of this project is to develop an analytical toolbox for detailed analysis of NMPs down to a size of 50 nm using chemical digestion & analysis for samples from municipal and industrial wastewaters and sluge/sediment, surface waters and sediment, groundwater and drinking‐water samples to support and risk exposure assessment studies and substance flow analysis modelling. The PhD candidate will optimize and combine different sample preparation and chemical treatment, field-flow fractionation, and mass spectrometry methods. NMPs of different shapes (fibres, spheres) and diverse chemistries (including fluoropolymers) with a focus on the nanosized plastics will be the focus of this work. For method development, reference materials of plastics in the nanosize range produced within the project (labelled materials) or at collaborators (e.g. Wetsus, Avantium BASF) will be used. The developed methods will be applied to the analysis of real samples (e.g environmental and (sea)food related).

What are you going to do?

You are expected to:

  • participate in the fundamental and/or applied research of our analytical-chemistry group, in close collaboration with IBEDs' environmental toxicology and HIMS' Industrial Sustainable Chemistry group;
  • develop fit-for-purpose sampling and sample treatment procedures for the efficient extraction of NMPs;
  • optimize a series of mass spectrometry and field‐flow fractionation‐based methods to detect, quantify and characterize of nano/microplastics (NMPs) including the smallest size fractions (< 1μm, down to 50 nm), which have so far been mostly ignored;
  • monitor exposure to NMPs through the water cycle and in drinking water;
  • publish and present your work within the project and on international scientific platforms;
  • contribute to the teaching activities of the department.

What do we require?

  • A recent MSc degree in Analytical/Environmental Chemistry and/or Polymer Chemistry;
  • demonstrated affinity with analytical separations;
  • ability to function in an international research team;
  • willingness to collaborate with BSc/MSc students, PhD candidates and postdoctoral researchers in related research projects and with other research groups within and outside the Netherlands;
  • good communication skills in oral and written English.

Our offer

We offer a temporary contract for 38 hours per week for the duration of 4 years (initial contract will be for a period of 18 months and after satisfactory evaluation it will be extended for a total duration of 4 years) and should lead to a dissertation (PhD thesis). We will draft an educational plan that includes attendance of courses and (international) meetings. We also expect you to assist in teaching undergraduates and Master students. 

The salary, depending on relevant experience before the beginning of the employment contract, will be €2,395 to €3,061 (scale P) gross per month, based on a full-time contract of 38 hours a week. This is exclusive 8% holiday allowance and 8.3% end-of-year bonus. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Dutch Universities is applicable.

Are you curious about our extensive package of secondary employment benefits like our excellent opportunities for study and development? Then find out more about working at the Faculty of Science.

    About the Faculty of Science and the Van't Hoff Institute for Molecular Science

    The Faculty of Science has a student body of around 7,000, as well as 1,600 members of staff working in education, research or support services. Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, be it elementary particles, the birth of the universe or the functioning of the brain.

    The Van't Hoff Institute for Molecular Sciences (HIMS) is one of eight institutes of the University of Amsterdam (UvA) Faculty of Science. HIMS performs internationally recognized chemistry and molecular research, curiosity driven as well as application driven. This is done in close cooperation with the chemical, flavour & food, medical and high-tech industries. Research is organized into four themes: Synthesis & Catalysis, Analytical Chemistry, Computational Chemistry and Molecular Photonics.

    The Industrial Sustainable Chemistry group and the analytical-chemistry group collaborate intensively with colleagues at the adjacent Institute for Biodiversity and Ecosystem Dynamics at UvA and with colleagues the Vrije Universiteit.

    Questions?

    Do you have questions about this vacancy? Or do you want to know more about our organisation? Please contact:

      Job application

      The UvA is an equal-opportunity employer. We prioritise diversity and are committed to creating an inclusive environment for everyone. We value a spirit of enquiry and perseverance, provide the space to keep asking questions, and promote a culture of curiosity and creativity.

      Do you recognize yourself in the job profile? Then we look forward to receiving your application by 17 May 2021. You may apply online by using the link below.

      Applications should include:

      • a motivation letter and CV, including a list of publications;
      • 2 letters of recommendations.

      We will invite potential candidates for interviews shortly after the vacancy is closed. The date and time will be indicated to the selected candidates via e-mail.

      We will recruit until a suitable candidate is found.



      DOC­TORAL STU­DENT, SPACE WEATHER AWARE­NESS TRAIN­ING NET­WORK

       

      The University of Helsinki (https://www.helsinki.fi/en) is an international scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities in Europe and ranks among the top 100 international universities in the world.

      The Department of Physics (https://www2.helsinki.fi/en/faculty-of-science/faculty/physics) offers the most varied university programme in the physical sciences in Finland. The department is large and multidisciplinary and employs about 200 people, of which 2 are academy professors (one of whom starting 1.9.2021), 17 are professors and 4 are associate and assistant professors. The research at the department and the research-based teaching follow a high international standard, are nationally significant, and promote the mental and economic wellbeing in society.

      The Department of Physics, Faculty of Science, University of Helsinki invites applications for a

      A DOCTORAL STUDENT position in the in the SWATNET Marie-Skłodowska-Curie Innovative Training Network

      POSITION DESCRIPTION

      The Space Weather Awareness Training Network (SWATNet) is a Marie - Sklodowska - Curie action Innovative Training Network (ITN) project. The project aims at breakthroughs in our physical understanding of the key agents of Space Weather. SWATNET educates 12 PhD students in the field of heliophysics with training led by experienced supervisors in a challenging, inherently international and interdisciplinary research environment. The consortium consists of nine Parties from eight European countries, as well as several recognized companies in the field. All students will be also introduced to the basics of solar observations at our partner observatory and conduct 1-3 months of industrial training. Please see https://swatnet.eu/ for further information on the project.

      The position announced here is in SWATNet Project 6, This project aims to investigate how CMEs evolve in the corona and quantify how this evolution depends on the magnetic structure of the CME, the instability responsible for the CME eruption and the properties of the source active regions. The project will combine state-of-the-art time-dependent magnetofrictional modelling and use extensive set of remote-sensing coronal observations.

      The selected student will pursue a PhD double degree awarded by University of Helsinki and Finland, and KU Leuven, Belgium https://www.kuleuven.be/english/. There is a 9 -months of compulsory period in KU Leuven (Secondment).

      ELIGIBILITY/REQUIREMENTS

      You need to be in the first four years (full-time equivalent) of your research career. You shall not have lived for more than 12 months in the last 3 years in Finland (Compulsory national service and short-time vacations do not count).

      Your previous degree must be relevant to the planned research topic and discipline. A degree is regarded as relevant if it includes sufficient studies in a discipline which, given the topic of the proposed doctoral dissertation, can be regarded as a suitable basis for doctoral studies. Education in space physics, space weather, plasma physics or similar field is required.You must have completed a Finnish second-cycle (master’s) degree or a foreign degree that makes you eligible for doctoral education in the country where the degree was completed. We require experience with Python and value experience in the analysis and visualization of three-dimensional datasets, experience with HPC, knowledge of solar observations.

      POSITION DESCRIPTION

      The Space Weather Awareness Training Network (SWATNet) is a Marie - Sklodowska - Curie action Innovative Training Network (ITN) project. The project aims at breakthroughs in our physical understanding of the key agents of Space Weather. SWATNET educates 12 PhD students in the field of heliophysics with training led by experienced supervisors in a challenging, inherently international and interdisciplinary research environment. The consortium consists of nine Parties from eight European countries, as well as several recognized companies in the field. All students will be also introduced to the basics of solar observations at our partner observatory and conduct 1-3 months of industrial training. Please see https://swatnet.eu/ for further information on the project.

      The position announced here is in SWATNet Project 6, This project aims to investigate how CMEs evolve in the corona and quantify how this evolution depends on the magnetic structure of the CME, the instability responsible for the CME eruption and the properties of the source active regions. The project will combine state-of-the-art time-dependent magnetofrictional modelling and use extensive set of remote-sensing coronal observations.

      You need to officially prove your academic level English language skills using the list of acceptable ways defined by University of Helsinki, read carefully the information and requirements on https://www.helsinki.fi/en/admissions-and-education/apply-doctoral-progr... (but attach the test to your application).

      SELECTION CRITERIA

      The student will be selected based on
      ● Scientific excellence, background and potential
      ● Scientific potential to carry successfully out the research in the project
      ● Success in undergraduate studies (in particular courses relevant to the field/topic, thesis grade)
      ● Reference letters
      ● Passion about science, motivation to conduct research in the field of heliophysics and work as a part of a big and vibrant international consortium
      ● Creativity and level of independence, interest for science communication.

      The applicants will be ranked and short-listed for the interview. The decision will be made by the Local Selection Committee and the SWATNET recruitment committee will oversee the process. The recruitment procedure of SWATNET follows the recommendations outlined by the European Charter for Researchers https://euraxess.ec.europa.eu/jobs/charter/european-charter and the Code of Conduct for the Recruitment of Researchers https://euraxess.ec.europa.eu/jobs/charter/code.

      SALARY AND BENEFITS

      The position is full-time and funded for three years. The salary is competitive and complies with the MSC Work Programme: 3500 euros per month before taxes, consisting of Living and Mobility allowance after compulsory deductions. A conditional Family allowance of 385 euros can be added to the salary.

      The University of Helsinki offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development. The International Staff Services office (https://www.helsinki.fi/en/university/working-at-the-university) assists employees from abroad with their transition to work and live in Finland.

      HOW TO APPLY

      Please submit your application with through the University of Helsinki Recruitment System via the link Apply for the position.

      The application shall include the following attachments as a single pdf file (in English):

      • Curriculum Vitae and List of Publications
      • Transcripts of your academic records (list and grades of the courses and BSc/MSc works)
      • Contact details for 2 referees (name, work address, phone, email)
      • Motivation letter
      • Indication of eligibility (read carefully from above).

      Applications will be given full consideration if received by May 7, 2021, 23:59 (CET). Applications received after this date will still be considered, until the position is filled.

      ADDITIONAL INFORMATION

      For more information on the position, please contact Professor Emilia Kilpua (emilia.kilpua(at)helsinki.fi).

      SWATNet project at the University of Helsinki https://swatnet.eu/?page_id=1209

      For more information on the Early Stage Researcher requirements and employment conditions in the MSC Work Programme, please visit
      https://ec.europa.eu/research/mariecurieactions/resources/document-libra....

      For more information on the Doctoral Programme in Particle Physics and Universe Sciences (PAPU), please visit https://www.helsinki.fi/en/admissions-and-education/apply-doctoral-progr...

      And here are some good reasons to move to Finland: http://www.stat.fi/tup/satavuotias-suomi/suomi-maailman-karjessa_en.html

      Due date

      07.05.2021 23:59 EEST


      PhD position Real World Evidence for Precision Drug Therapy (1.0 FTE) (221169)

       

      In the unit of Pharmacotherapy, Epidemiology and Economics (PTEE) of the Groningen Institute for Pharmacy (GRIP: http://www.rug.nl/grip) we are looking for a PhD candidate for a project in the area of Precision Drug Therapy. Precision drug therapy is a new and rapidly growing field that combines biomedical science, statistics, and machine learning. The ambitious goal of precision drug therapy is to identify optimal treatment strategies for patient subpopulations. You will seek to identify these subpopulations, the optimal treatment within those subpopulations, and possibly gain insight into the causes of diversity in patient response. To do this, you will make use of advanced statistical procedures embedded in the causal inference (potential outcomes) framework together with machine learning methods, applied to rich patient databases (see organisation, below). Such databases can include demographic and physiological measurements, genetic and genomic information, co-morbid conditions, individual patient preferences, adherence, lifestyle, and more.

      Responsibilities and tasks:

      • identifying relevant patient subpopulations or treatment trajectories
      • identifying causal treatment effect heterogeneity
      • writing scientific articles and conference communications
      • participation in acquiring additional funds for this research line
      • teaching activities (10% of total workload), mostly on supervision of bachelor and master students
      • contribute to the scientific and collaborative research environment in the unit of Pharmacotherapy, Epidemiology and Economics (PTEE).

      Qualifications

      We are looking for a motivated and skilled student with an MSc degree in Pharmacy, Biomedical Sciences, Medicine, or related disciplines. High grades on statistics courses are an advantage, as is familiarity with a statistical programming language, but these are not requirements for application. The successful candidate must be motivated to become a 'pharmaceutical data scientist', and as such should be interested in learning advanced statistical and machine learning methods (under supervision). The candidate will learn and work with a statistical programming language (e.g. R or Python, but if desired by the candidate others such as Julia, C++, etc. are also possible). Excellent verbal and written communication skills in English are important.

      Organisation

      The University of Groningen has an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Balanced study and career paths in a wide variety of disciplines encourage the 35,000 students and researchers to develop their own individual talents. Belonging to the best research universities in Europe and joining forces with prestigious partner universities and networks, we are truly an international place of knowledge.

      The Faculty of Science and Engineering harbours a kaleidoscope of disciplines and research strengths. Our programmes in research and education range from nanomaterials and biomachinery to astronomy, from mathematics to pharmacy, from neurosciences to computer science, and from molecular and evolutionary biology to marine biology.

      The vacancy is set in the unit PharmacoTherapy, -Epidemiology & -Economics of the Groningen Research Institute of Pharmacy (GRIP: http://www.rug.nl/grip). The successful candidate will join a dynamic, multidisciplinary, group of researchers in this department, stemming from the disciplines of pharmacotherapy, pharmacogenetics, pharmacoeconomics, clinical pharmacology, clinical pharmacy, and clinical pharmacoepidemiology. We are active in research focusing on studies using “real world” health care data. We have access to various databases and recently started a collaboration with the Lifelines cohort study, genetic department and our in-house prescription database IADB.nl called Pharmlines Initiative.

      Conditions of employment

      We offer you, following the Collective Labour Agreement for Dutch Universities:

      • a salary of € 2,395 gross per month in the first year, up to a maximum of € 3,061 gross per month in the fourth and final year for a full-time working week
      • a holiday allowance of 8% gross annual income
      • an 8.3% year-end bonus
      • a full-time position (1.0 FTE) for 4 years
      • a position for four years; first, you will get a temporary position of one year with the option of renewal for another three years; prolongation of the contract is contingent on sufficient progress in the first year to indicate that successful completion of the PhD thesis within the contract period is to be expected.

      A PhD training programme is part of the agreement and you will be enrolled in the Graduate School of the Faculty of Science and Engineering.

      Starting date is flexible; the ideal starting date is during or before the fourth quarter of 2021.

      Application

      Do you meet our qualification criteria? If yes, your application should include:

      • cover letter (1 to 2 pages)
      • curriculum vitae
      • transcripts from your bachelor’s and master’s degree
      • a short research statement describing what you wish to study and why (up to 1 page).

      You can submit your application until 30 May 11:59 / before 31 May 2021 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

      We are an equal opportunity employer and value diversity at our University. We are committed to building a diverse faculty so you are encouraged to apply. Our selection procedure follows the guidelines of the Recruitment code (NVP), https://nvp-plaza.nl/download/?id=7714 and European Commission's European Code of Conduct for recruitment of researchers, https://euraxess.ec.europa.eu/jobs/charter/code

      Unsolicited marketing is not appreciated.

      Information

      For information you can contact:

      Please do not use the e-mail address(es) above for applications.

      Apply



      PhD position in Multiscale Modeling of Supramolecular Materials (221139)

       

      Supramolecular and hybrid nanomaterials are attracting much interest in view of their potential applications in various branches of engineering. New experimental techniques are offering unprecedented opportunities in the design of new materials at the molecular scale, vastly outperforming materials currently in use. Yet, the exploration of the huge design space is a severe bottleneck, and computational models are needed to provide quantitative, predictive guidelines for material design. Multiscale modeling is required in order to bridge the spatiotemporal gap between computer simulations and engineering applications and to capture emergent behaviour at several scales.
      Polymeric materials offer great flexibility in their molecular design. Complex new materials made of branched polymers or polymer nanocomposites have been recently emerging for novel medical and industrial applications thanks to their tunable properties, but the prediction of their macroscopic behaviour remains vastly unexplored from a computational point of view, particularly in out-of-equilibrium conditions of interest for experimental applications.
      The aim of this project is to use molecular dynamics simulations to link polymer architecture and functionality at the molecular scale to the material’s macroscopic properties like self-organisation, dynamics, and mechanical response. Our goal is to develop predictive models at multiple scales to bridge the gap between simulations and experiments. The project is highly interdisciplinary, with possible collaborations with several experimental groups in the Faculty of Science and Engineering.
      As a PhD candidate, you are committed to conduct independent and original scientific research, to report on this research in international publications and presentations, and to present the results of the research in a PhD dissertation, to be completed within 4 years. You are expected to contribute 10% of the overall workload to teaching.

      Qualifications

      You are a highly motivated candidate with:

      • a MSc degree in physics, chemistry, engineering or other relevant subjects
      • strong interest in computational research and material science
      • demonstrable affinity with programming and/or computer simulations
      • strong communication skills (in English).

      Organisation

      Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage more than 35.000 students and researchers alike to develop their own individual talents.

      This position is embedded in the micromechanics group of the Zernike Institute for Advanced Materials, at the interface between physics, chemistry, biology and engineering. The mission of the micromechanics group is to develop new models and computational tools for the micromechanics of (bio)materials, and to employ these to develop relationships between the internal structure of a material and its mechanical and functional properties. More information on the Institute’s activities can be found at http://www.rug.nl/research/zernike/.

      Conditions of employment

      We offer in accordance with the Collective Labour Agreement for Dutch Universities:

      • a salary of € 2,395 in the first year to a maximum of € 3,061 gross per month in the final year (PhD salary scale), based on a full-time position
      • a holiday allowance of 8% gross annual income and an 8.3% year-end bonus
      • a position for four years. First you will be offered a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate whether a successful completion of the PhD thesis within the contract period is to be expected. A PhD training programme is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering of the Faculty.

      The conditions of employment are available at the University of Groningen website under Human Resources: https://www.rug.nl/about-us/work-with-us/

      The starting date is in October 2021 or shortly thereafter

      Application

      Do you meet our qualification criteria? If yes, your application should include (please merge all documents into one PDF file and upload it as 'your letter of motivation'):

      • a cover letter with background and motivation to apply for this position (max 1 page)
      • a curriculum vitae, including details of Bachelor and Master degrees, list of work experience as well as other skills and a publication list, if applicable
      • a detailed (max 1 page) description of previous research experience, such as Bachelor/Master research projects. Indicate exactly your contribution
      • contact details of 2 academic references who can provide information on your suitability for the position.

      You may apply for this position at least until 31 August 11.59 pm / before 1 September 2021 Dutch local time (CET) by means of the application form (click "Apply" below the advertisement on the Groningen University website). The applications will be separately considered as soon as possible after the submission and the application form will remain active until the position is filled.

      We are an equal opportunity employer and value diversity at our University. We are committed to building a diverse faculty so you are encouraged to apply. Our selection procedure follows the guidelines of the Recruitment code (NVP), https://nvp-plaza.nl/download/?id=7714 and European Commission's European Code of Conduct for recruitment of researchers, https://euraxess.ec.europa.eu/jobs/charter/cod.

      Unsolicited marketing is not appreciated.

      Information

      For information you can contact:

      Please do not use the e-mail address(es) above for applications.

      Apply



      PhD positions in enzyme engineering and biocatalysis (2.0 FTE) (221156-57)

       


      In order to pursue our research activities, we are looking for two highly motivated PhD candidates who will contribute to an EU-ITN project called CC-TOP (https://cc-top-itn.eu/cc-top-project/). The main goal of CC-TOP is to train the next generation of multi-disciplinary researchers in order to boost the development and exploitation of carboligation enzymes for industrial biotechnology, in particular for production of fine chemicals and pharmaceuticals. Therefore, CC-TOP will train 15 Early Stage Researchers (ESRs) in a mosaic of disciplines and technologies around enzymatic carboligation and its translation into industrial application. The network´s aim for efficient translation of breakthrough technology into industrial application is emphasised through the implementation of an industrial skills module and measures for active innovation management involving all ESRs. The two individual ESR projects at the University of Groningen are described below.

      PhD project (ESR13) on exploiting enzyme promiscuity to develop novel aldolases
      ESR13 investigates 4-oxalocrotonate tautomerase (4-OT) promoted aldol addition of acetaldehyde to a variety of benzaldehydes looking for efficiency, stereochemistry and product selectivity. The researcher will generate mutability landscapes for this enzyme to develop tailor-made aldolases with enhanced activity and selectivity and will harness the best performing enzymes in (chemo)enzymatic cascades to prepare diols and aminoalcohols. In addition, redesigned natural aldolases will also be tested as potential catalysts for these and related reactions. Moreover, the researcher will oversee characterisation studies of these enzymes. Research training periods (secondments) of a few months at Prozomix Ltd (UK) and TU Darmstadt (Germany) are foreseen.

      PhD project (ESR14) on engineering of enantioselective Michaelases
      ESR14 investigates the promiscuous activity of 4-OT and related enzymes to promote the asymmetric addition of nitroalkanes to a wide variety of α,β-unsaturated aldehydes. For this purpose, the researcher enrolled will optimise the enzymes for reactions that yield interesting γ-aminobutyric acid (GABA) precursors by using different tools of protein engineering. He/she will afterwards characterise the artificial Michaelases in terms of structure-function relationships, using techniques such as DNA sequencing, protein purification and characterisation, and X-ray structure analysis. Research training periods (secondments) of a few months at the University of Zagreb (Croatia) and Enzymicals AG (Germany) are foreseen.

      Qualifications

      We are looking for enthusiastic and talented PhD candidates with a Master of Science (MSc) degree in chemistry, biotechnology, biochemistry, or related, and with outstanding laboratory skills. Experience with chemical synthesis and analysis is a big plus. You are expected to have an excellent academic record and be fluent in the English language. Important personal skills include the ability to collaborate with a variety of (external) parties, and be interested in further exploration of commercial applications.

      IMPORTANT: PhD candidates must not have resided or worked for more than 12 months in the Netherlands in the last 3 years before the start of their contract and will have a maximum of 4 years of experience after graduation.

      Organisation

      The vacancies are at the Department of Chemical and Pharmaceutical Biology (Prof. Gerrit J. Poelarends; http://www.rug.nl/staff/g.j.poelarends/), Groningen Research Institute of Pharmacy, Faculty of Science and Engineering, University of Groningen. The research of Prof. Poelarends is aimed at the design of novel biocatalysts and enzymatic cascades for the synthesis of pharmaceuticals and food additives. We offer a stimulating research environment for PhD students interested in enzyme engineering and biocatalysis. The department’s research laboratories are well equipped for molecular biology, enzymology, protein engineering, biocatalysis, and organic chemistry work.

      The University of Groningen (founded in 1614) has a long tradition of academic excellence, being one of the oldest research universities in Europe. The University is currently in or around the top 100 on several influential ranking lists. Currently approximately 35,000 students are enrolled and about 1,500 PhD students work on their theses. It has a highly international character: English is the main language in the research laboratories. The city of Groningen is a historic town and among the ten biggest cities in The Netherlands. It is a vibrant student town with a direct train connection to Schiphol Airport near Amsterdam.

      Conditions of employment

      We offer you in accordance with the Collective Labour Agreement for Dutch Universities:

      • a salary of € 2,395 (salary scale PhD candidates) gross per month in the first year, up to a maximum of € 3,061 gross per month in the fourth and final year, based on a full-time position
      • a holiday allowance of 8% gross annual income an 8.3% year-end bonus
      • a temporary position of one year with the option of renewal for another three years; prolongation of the contract is contingent on sufficient progress in the first year to indicate that you will successfully complete your PhD thesis within the next three years. A PhD training programme is part of the agreement.

      The preferred starting date is between September 2021 and November 2021.

      Application

      Submit your application via the CC-TOP website: https://cc-top-itn.eu/cc-top-project/

      Required documents: curriculum vitae, motivation letter, certified records, names and email addresses of at least two academic references willing to write confidential letters of recommendation.

      We are an equal opportunity employer that values diversity. We have adopted an active policy to increase the number of female scientists across all disciplines of the university. Therefore, women are encouraged to apply. Our selection procedure follows the guidelines of the Recruitment code (NVP), https://www.nvp-hrnetwerk.nl/sollicitatiecode/ and European Commission's European Code of Conduct for recruitment of researchers, https://euraxess.ec.europa.eu/jobs/charter/code

      Deadline for the applications is 31 May 2021, 11:59 pm (CET).

      Information

      For information you can contact:

      Please do not use the e-mail address(es) above for applications.


      PhD positions in biochemistry, biophysics and structural biology (3.0 FTE) (221160-62)

       


      The 3 PhD candidates with backgrounds in biophysics or biochemistry will conduct curiosity-driven biomolecular research to investigate the working mechanism of an ABC transporter involved in cell volume regulation, using high-resolution cryo-electron microscopy, single-molecule fluorescence and biochemical assays, and develop methods to study protein networks in synthetic membrane systems. The research will be performed in the groups of Cristina Paulino and Bert Poolman of the Groningen Biomolecular Sciences and Biotechnology Institute. There will be significant interactions and collaborations between the 3 PhD students, other team members and international colleagues (e.g. in the context of the EU program BioInspireSensing). In addition to conducting research, there will be some teaching duties (~10% of your time).

      Project
      One of the outstanding questions in biochemistry and cell biology relates to the control of cell volume during growth and under environmental stress. We have found a new structural element located in the ABC transporter OpuA that may act as the ionic strength sensor and allow the transporter to be gated by osmotic stress. In addition, we have found that the 2nd messenger cyclic-di-AMP can act as a safety check for OpuA and prevent the unbridled uptake of solutes under conditions that the cell is in danger of lysis. We now aim to elucidate the full mechanism of transport of OpuA (two PhD positions with main focus on structure and function, respectively) and study the protein in the context of a synthetic network with control of vesicle volume via a mechanosensitive channel protein (one PhD position).

      Qualifications

      The candidates are expected to have a (research) Master’s degree in biophysics, biochemistry and/or molecular biology, and a strong interest in unravelling the structure-function relationship that underlies the transport mechanism of proteins. Experience with membrane proteins and protein chemistry in general, and depending on the distinct positions - experience with functional assays and fluorescence microscopy, or structural biology (specifically electron microscopy) are a plus. You have good teamwork skills, a “can-do” mentality, are perseverant and have excellent communication skills in English.

      Organisation

      Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study program and academic career opportunities in a wide variety of disciplines encourage the 35.000 students and researchers alike to develop their own individual talents. The University is in the top 100 on several influential ranking lists.

      Groningen Biomolecular Sciences and Biotechnology Institute, Faculty of Science and Engineering
      The Groningen Biomolecular Sciences and Biotechnology Institute is a center for top-noted research and teaching in biomolecular sciences, hosting the subdisciplines biochemistry, bioinformatics, biophysical chemistry, cell biology, chemical biology, enzymology, genetics, microbiology, computational modeling, and systems biology. The focus is on curiosity-driven science, with application outlets into (industrial) biotechnology and biomedicine.

      Conditions of employment

      The conditions of employment are in accordance with the Collective Labour Agreement for Dutch Universitiesare and available at:

      https://www.rug.nl/(...)-employment?lang=eng At our faculty, a PhD project takes four years, during which the PhD student receives a salary. In addition, our PhD’s receive an annual training budget of € 675 to be spent on courses, conferences, etc.

      The preferred starting date should be between July and September 2021.

      Application

      Do you want to become a member of our team? Please send your application to us, by submitting the following requested documents:

      • a motivation letter, in which you indicate your interest in one of the PhD position
      • a complete curriculum vitae
      • names and email addresses of two referees
      • if available, an example research paper with a brief explanation on what sparked your interest.

      You can submit your application until 31 May 11:59 pm / before 1 June 2021 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

      We are an equal opportunity employer and value diversity at our University. We are committed to building a diverse faculty so you are encouraged to apply. Our selection procedure follows the guidelines of the Recruitment code (NVP), http://nvp-plaza.nl/download/?id=7714 and European Commission's European Code of Conduct for recruitment of researchers, https://euraxess.ec.europa.eu/jobs/charter/code

      Unsolicited marketing is not appreciated.

      Information

      For information you can contact:

      Please do not use the e-mail address(es) above for applications.

      Apply




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      Federation University Australia in Australia invites application for vacant (14) Academic Positions