Postdoctoral Researcher in Metabolic Engineering in RNA virus infection

 

The Department of Laboratory Medicine consists of seven divisions and is engaged in advanced basic scientific, clinical, and epidemiological research. The department is also one of the largest education departments at Karolinska Institutet. A postdoctoral position is now available at the Systems Virology Lab, Division of Clinical Microbiology.

The research

The Systems Virology lab aims to identify the molecular mechanism of host-viral response against RNA viruses using multi-omics technologies and experimental assays. We aim to identify the components of the immune response that are required for natural immune protection and linked with disease severity that can be translated into the future development of vaccine and antiviral strategies against emerging and re-emerging viruses. The research team has both bioinformatics and experimental teams and works in an interdisciplinary research environment. The present postdoctoral position is towards understanding the host-viral interactions in RNA virus targeting HIV-1 and SARS-CoV-2 and developing antiviral strategies through metabolic engineering. The potential candidate is encouraged to look into the group website https://ki.se/en/labmed/the-systems-virology-lab

Your mission

Are you interested to learn how our immune system interacts with viruses and can we explore virus weakness to eliminate it? We are looking for a Post-Doctoral researcher for our research theme, the correlates of immune protection against RNA viruses, who will work mainly to understand the immune-metabolic modulation during acute or chronic viral infection.
A major focus of the work will be on virus-host cell interaction and to determine the signaling pathways that drive virus-induced disease biology in HIV-1 and SARS-CoV-2. The ideal candidate will possess exceptional skills in virology, multi-color flow cytometry, and/or cell biology.
Preference will be given to those who worked with the BSL3 viruses and immune modulation of cellular pathways in the cell lines and primary cells. Expertise in the field of metabolism, loss-of-function screens and reverse viral genetics including CRISPR-Cas9 would represent a major advantage.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The ideal candidate will be two years after receiving the doctorate who can qualify to apply for funding for start-up grants from Swedish or European Union within couple of years.
Please read the qualification in https://staff.ki.se/information-about-researching-as-a-postdoctoral-researcher

The candidate should have achieved the corresponding scientific competence, with first-authored publications in internationally leading journals in the immunological fields with strong knowledge in developing high-dimensional multi-color FACS panels, loss-of-function screens and reverse viral genetics.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

The group has experience with two Swedish Research Council Establishment grants and several grants for Young Investigators. We will provide mentorship for applying grants potentially in own line of research within the field of emerging, re-emerging RNA viruses and encourage to use several grants. 

Research Group:

The postdoctoral position is available in the Systems Virology Lab, Division of Clinical Microbiology, Department of Laboratory Medicine in Huddinge (KI South Campus, Flemingsberg). The candidate may have to travel to US and Germany to the collaborators' laboratory for some of the assays.

Location: Flemingsberg

Read more about the Department of Laboratory Medicine

Read more about the Division

Read more about the Research Group

Application

An employment application must contain the following documents in English or Swedish:

- A cover letter
- A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
- A complete list of publications
- A summary of current work (no more than one page)

Welcome to apply at the latest 2022-04-30

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Type of employment	Temporary position longer than 6 months
Contract type	Full time
First day of employment	According to agreement
Salary	Monthly
Number of positions	1
Working hours	100%
City	Huddinge
County	Stockholms län
Country	Sweden
Reference number	STÖD 2-766/2022
Contact	Research Group leader, Ujjwal Neogi, ujjwal.neogi@ki.se
Union representative	Carina Eklund, OFR, carina.eklund@ki.se Emilie Hultin, SACO, emilie.hultin@ki.se Henry Wölling, SEKO, henry.wolling@ki.se
Published	16.Feb.2022
Last application date	30.Apr.2022 11:59 PM CEST

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PhD student position in cancer computational biology

 

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Hausser lab researches quantitative principles in tumor biology. We do so along two research lines.

(1) Within a tumor, single cancer cells express different genes. These differences facilitate resistance against anti-cancer therapy because a given therapy may fail to eliminate the diversity of cancer cells. We are interested in mapping the evolutionary limits of this diversity, and in exploring how to exploit these limits to treat heterogeneous tumors.

(2) We research equations that state how key tumor properties relate to each other: cellular composition of the tumor, heterogeneity of cancer and immune cells found in the tumor, spatial organization, tumor growth rate, shedding rate of metastatic cells, and so on. Finding the laws of tumor biology has high potential for diagnostics, prognosis and to design immunotherapy, much like the laws of mechanics and aerodynamics presently support the design of cars and airplanes.

To do so, we perform cancer experiments in vitro and in vivo, we develop bioinformatics & data analysis, and articulate our findings into mathematical theory.

The lab is part of the department of Cell and Molecular Biology (CMB) is located in Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna under one roof to promote collaboration. Biomedicum houses approximately 1,200 researchers and other personnel and allows expensive equipment to be shared and utilised more effectively.

https://www.hausserlab.org

The doctoral student project and the duties of the doctoral student

You will investigate the interplay between the transcriptional heterogeneity of tumor cells, their fitness, and the spatial architecture of tumors. Specifically, what gene programs support the fitness of cancer cells in the different environments found in tumors? Can we formulate combination therapy that interfere with genes across environments to treat heterogeneous tumors?

To find out, you will analyze single-cell RNAseq and spatial transcriptomics data from patients. You will culture 3D tumor spheroids, perform single-cell RNAseq, CRISPR screening, flow cytometry and single cell sorting. You will use bioinformatics tools and multivariate statistics to analyze the data, as well as develop new approaches. You will articulate the patterns found into a mathematical theory. You will use the insight won to design treatments aimed at heterogeneous tumors, test these in vitro and validate them in vivo.

What do we offer?

Exciting science in a lab ideally positioned for you to learn how to do research at the interface between experimental and computational biology, in an area of direct medical relevance.

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

- Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

- We seek a student with a solid quantative education covering multi-variate calculus, linear algebra, ordinary and partial differential equations, dynamical systems theory, probability theory, at the level granted by a Masters-level education in computational biology, physics or engineering.
- The candidate should have a good team spirit and a keen interest in discovering quantitative principles in biology and in cancer.
- The candidate should be skilled in R and Python programming, be familiar with the Linux environment.
- Experience with multivariate statistics and mathematical modeling will be valued (within biology a plus).
- Prior practical experience with single-cell gene expression data, cancer and evolution is a strong plus.
- Familiarity with cell biology, cancer biology, immunology and practical experience with performing experiments on cells is a strong plus.
The student is required to have good communication skills in English (written and verbal). Ability to work in teams will be highly valued.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

--[Video about Karolinska Institutet, how we all work towards "a better health for all"] -

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

- A personal letter (1-2 pages) that includes answers to these questions: what course or projects did you most enjoyed in your studies so far, and why? If you could choose any topic, what would you like to work on in the future? What’s the most interesting research question you’ve worked on so far, what methods have you used to answer these questions, and what have you found?
- A curriculum vitae
- Degree projects and previous publications, if any
- Any other documentation showing the desirable skills and personal qualities described above
- Documents certifying your general eligibility (see A above)
- Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

- Documented subject knowledge of relevance to the area of research
- Analytical skill
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

 

Want to make a difference? Join us and contribute to better health for all

Type of employment	PhD placement
Contract type	Full time
First day of employment	According to agreement
Salary	Monthly salary
Number of positions	1
Working hours	100
City	Stockholm
County	Stockholms län
Country	Sweden
Reference number	STÖD 2-1298/2022
Contact	Jean Hausser, PhD,, jean.hausser@ki.se
Union representative	Taher Darreh-Shori, SACO, taher.darreh-shori@ki.se Magnus Anå, OFR, 08-52486437,magnus.ana@ki.se Elisabeth Valenzuela, SEKO, 08-52486353
Published	25.Mar.2022
Last application date	24.Apr.2022 11:59 PM CEST

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Postdoctoral researcher to study synergistic effects between DNA damaging cancer therapeutics and targeted agents for an industrial collaboration

 

The Helleday laboratory, at the Department of Translational Medicine and Chemical Biology, is located at SciLifeLab and consists of about 30 researchers, doctoral students, and postdocs. Our goal of the business is to improve current cancer treatment by utilizing defects in cancer cells to tailor specific drugs against all types of cancer, with minimal side effects. Our work includes both basic research and translational research and we have several collaborations between different disciplines. The research group is multidisciplinary with expertise in cell biology, biochemistry, drug chemistry and pharmacology from both academia and industry.

Your mission

Cancer is often characterized by genome instability which is one of the enabling characteristics of cancer. Along the progression of cancer, mutations occurring in the genome maintenance and surveillance systems endanger the integrity of the genome. This genome instability results in new mutations and genomic rearrangements driving cancer progression via selection of favourable phenotypes. However, genomic instable cancer cells are more vulnerable to DNA damage than non-malignant cells since their DNA repair machinery often is deficient. This cancer cell vulnerability, along with the high proliferation rate of cancer cells, enables the usage of DNA damaging cancer treatment, such as ionizing radiation and chemotherapy, which have been used in cancer treatment for nearly a century.

The goal of targeted cancer therapy is to selectively kill cancer cells based on their molecular survival mechanisms. DNA repair is as a promising cancer target as many cancers have chronic replication stress and deficiencies in the DNA damage response. Moreover, combining DNA damaging chemo- and radiotherapy with inhibitors of DNA repair can lead to improved treatment responses, reduced resistance to treatments, as well as lowering of effective doses and thereby reduced toxicity to healthy tissues. We have characterized new factors regulating DNA damage repair that can be harnessed for targeted cancer therapy approaches, and now seek to find synergistic interactions between our drug candidates and current chemotherapeutics as well as radiation therapy to optimize drug partners for future cancer therapy.

We are seeking a postdoctoral researcher who will investigate the synergistic effects of currently used chemotherapeutics and radiation therapy between new targeted cancer drug candidates. The candidate will work in tight collaboration between the Helleday laboratory and an industrial partner.

Your profile

Applicants must have a doctorate degree in cancer molecular biology and prior experience in cancer drug development is highly appreciated. We prefer applicants to have experience in working with chemotherapeutics and ionizing radiation as well as targeted cancer therapeutics. Candidates must have expertise in conducting drug synergy assays with cancer cell lines and excellent mammalian cell culture skills.

Applicant should have a degree of theoretical knowledge on the DNA damage response (DDR) including DNA repair pathways, especially homologous recombination repair and Fanconi Anemia repair. Moreover, applicant should understand the mechanisms of action of main cancer therapeutics. In addition, the candidate should have practical knowledge on molecular methods to study DDR including experience and skills in basic molecular biology methods such as flow cytometry, western blotting and confocal microscopy.

Furthermore, the candidate must have very good knowledge of the English language and be able to express themselves both orally and in writing in a professional manner. Understanding Swedish is a plus. The role requires experience in project management, analytical thinking and excellent documenting and presentation skills. It is an advantage if applicants have research experience from abroad. Good interpersonal skills and prior work in an industrial setting are desirable.

 It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

 

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page) 

Welcome to apply at the latest March 18th. 

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Type of employment	Temporary position longer than 6 months
Contract type	Part-time
First day of employment	As per agreement
Salary	Monthly
Number of positions	1
Working hours	50%
City	Solna
County	Stockholms län
Country	Sweden
Reference number	STÖD 2-1028/2022
Contact	Athina Pliakou, +46 70 213 57 63, athina.pliakou@ki.se
Published	04.Mar.2022
Last application date	18.Apr.2022 11:59 PM CEST

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Postdoctoral Researcher in Risk and Resilience in Neurodevelopmental Conditions using the ICF system

We are seeking a postdoctoral researcher with a strong passion for conducting research that strives to contribute to the quality of life and mental wellbeing of individuals with Neurodevelopmental Conditions. As part of a European consortium - Risk and Resilience in Developmental Diversity and Mental Health (R2D2-MH) – we are conducting research which aims to improve the mental health outcomes of young people with these challenges. The postdoctoral position will examine the factors related to risk and resilience for adverse health and psychosocial outcomes in by developing International of Classification of Functioning (ICF) core sets for risk and resilience in this population. In addition, the postdoc interacts with researchers in the European Consortium and contributes to other work packages investigating resilience.

The research group
KIND, Karolinska Institutet Center of Neurodevelopmental Disorders, located in the heart of Stockholm, is a leading competence center for research, development, education, and practice within the area of neurodevelopmental conditions. KIND is established in collaboration between Karolinska Institutet and Region Stockholm research aiming at improving clinical practice and the community for neurodivergent people and their families. We are a diverse team of around 50 researchers and enthusiastic clinicians sharing the vision of the center and want you to join us.

For more information about KIND please visit: https://ki.se/en/kind/center-of-neurodevelopmental-disorders-at-karolinska-institutet-kind

Your mission

This 3-year postdoctoral position will contribute to the outcomes R2D2-MH. Based on a multiscale study of resilience factors - from biology to psychological and societal factors, R2D2-MH will provide innovative approaches to increase the quality of life of individuals with Neurodevelopmental Disorders. KIND is one of 22 consortium members of R2D2-MH contributing to this aim.

Your postdoctoral position will focus on the co-creation of ICF Core sets - shortlists of ICF codes - for risk and resilience in neurodevelopmental conditions, identifying the most significant and shared factors related to risk and resilience for adverse health and psychosocial outcomes in Neurodevelopmental Disorders. The development of these ICF core sets will involve a systematic review of the resilience and risk literature using corpus methods, an internal expert survey, a qualitative study with multiple stakeholders, real-life domain studies of persons with neurodevelopmental conditions. The developed core sets will be used to derive diagnostic tools, test batteries and quantitative scales for risk and resilience assessment. You will also work to link databases formed as part of the broader project to the ICF and will interface with other work packages of R2D2-MH.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

It is a requirement that your doctorate (or equivalent) be within a subject area of relevance to neurodevelopmental disorders, and it is highly desirable that you have documented experience with the ICF, including familiarity with ICF linking methodologies as outlined by the World Health Organization (WHO). Experience in both quantitative and qualitative research methodologies, especially related you psychometrics and instrument development/evaluation, including excellent skills in working with standard data analytic software is required, with experience in co-production and co-design methodologies also considered a merit. As this project requires communication and interaction with multiple stakeholders abroad, a high level of proficiency in verbal and written English is also necessary. As a postdoctoral researcher, you should have a developing record of accomplishment, demonstrated by the publication of research outputs in high quality refereed academic journals/outlets consistent with the discipline.

We expect you to contribute actively and constructively to the development of our projects and that you have great collaborative ability. You are expected to be able to work both team-based as well as on your own. The preferred candidate will be motivated, responsible, and hardworking.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Learn more about Department of Women's and Children's Health here

Location: Solna

 

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply! 

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Type of employment	Temporary position longer than 6 months
Contract type	Full time
First day of employment	according to agreement
Salary	monthly salary
Number of positions	1
Working hours	100%
City	Solna
County	Stockholms län
Country	Sweden
Reference number	STÖD 2-1066/2022
Contact	Sven Bölte, Professor, sven.bolte@ki.se Johanna Ahlström, HR-Partner, 08-524 823 97
Union representative	Henry Wölling, SEKO, henry.wolling@ki.se Bodil Moberg , OFR, 08-524 836 01 John Inge Johnsen , SACO, John.Inge.Johnsen@ki.se
Published	09.Mar.2022
Last application date	18.Apr.2022 11:59 PM CEST

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Postdoctoral Researcher in Molecular and Translation Lung Cancer Research

 

We are seeking a Postdoctoral Researcher (Scholarship) with an interest in lung cancer biology/therapy. You should hold great prior knowledge in tumor biology and it is preferred that you already are familiar with extracellular vesicles (EVs) research. When joining us you will work in a multidisciplinary environment, close to frontline preclinical/translational/clinical lung cancer research but also in context of radiation therapy as well as with our partners on microchip technology for EVs characterization.

For more information of Department of Oncology/Pathology information is given here:

 Department of Oncology-Pathology

More information about the Team Lewensohn research line is given here:

Research team Lewensohn Viktorsson Lindberg

Division

You will work in the Ekman research group, Team Lewensohn, and in particular in our preclinical research which focus on EVs analyses in lung cancer. You will in particular work with EVs as a signalling component in context of mutated EGFR, Ephrin/Eph growth factor receptor signalling and prior and post radiation therapy. The work will be carried out in lung cancer cell line models in vitro but with validation in clinical samples from lung cancer patients.

Duties

You will together with the team set up a project on EVs to decipher their role in resistance to EGFR-TKI treatment and in particular to understand the role of the Ephrin and Eph signalling network in this context. You will design and carry out experiments, in an independent way, on EVs in this context using lung cancer cell line models and front-line technologies . You will use EVs from clinical liquid biopsies (e.g. plasma, serum and pleura effusion fluids) to validate the clinical relevance of your preclinical results. You will also be part of a preclinical validation project on markers identified in EVs from patient plasma/serum or pleura effusion fluid in relation to radiation therapy or EGFR-inhibitors. 

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year-period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Other requirements

We are looking for you who holds a PhD degree from a University outside Sweden. We want to recruit you who have made a thesis work related to tumour biology and we are in particular seeking you with prior knowledge on EV analytics. You need to be able to independently carry out standard cell- and molecular- biology techniques such as cell culture work, tumour treatment, siRNA transfection, flow cytometry, western blotting, immunofluorescence etc. It is clearly an advantage if you have worked with EV analytics previously.

Type of scholarship

Full time contract with Scholarship for a first six-month period with possible prolongation. The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable. 

Application process

An application must contain the following documents in English:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page) and its relation to the advertised position
• A one-page description on technology skills with emphasize on the advertised position and your capacity to independently carry out/evaluate results from these.
• Letter of recommendation and contact information (email and phone) to two references (which has agreed to be reference)

The application is to be submitted on the Varbi recruitment system on the 15th of April at the latest.

Assessment criteria

The entry requirements for scholarship postdoc is indicated above. Apart from these the following criteria will be assessed and form the basis for selection of candidates to personal interview for the position.

• PhD degree in the tumor biology or exosome field (assessed by CV)
• Fluent in written and spoken English (assessed by CV)
• At least two 1st author paper in a cancer-linked journal with peer review process (assessed by publication list submitted with the application)
• Demonstrated skills in cell culture work, tumour treatment, siRNA transfection (assessed by CV and/or publications submitted with the application)
• Personal qualifications and research interest/plan (assessed by personal letter in application)

It is particularly meritorious that the applicant has:

• Previous experience in working in translational cancer research (assessed by publication list submitted with the application)
• Skills and independently can work with technologies such as flow cytometry, western blotting, immunofluorescence (assessed by publications and/or CV)
• Methodological experience in EV analytics (assessed by publication list submitted with the application)
• Experience in Electronic Lab Book documentation which is a prerequisite at KI for all research (assessed by CV and personal letter)
• Previous experience from working abroad in other labs than where the PhD degree lab was obtained (assessed by CV)

After an overall assessment of the expertise and merits of the applicants in relation to the subject area and personal interview of candidates, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

Want to make a difference? Join us and contribute to better health for all

First day of employment	15th of May
Salary	Semi-annualy
Reference number	STÖD 2-1295/2022
Contact	Kristina Viktorsson, kristina.viktorsson@ki.se Rolf Lewensohn, Rolf Lewensohn@ki.se
Published	22.Mar.2022
Last application date	15.Apr.2022 11:59 PM CEST

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