Postdoctoral Fellow - Structural biology of Plasmodium falciparum membrane complexes

 


We are seeking for a highly motivated structural biologist with cryo-EM expertise to study membrane complexes of the malaria parasite Plasmodium falciparum. The research portfolio of the Hamburg Unit is mainly focused on structures of membrane proteins and large protein complexes by diverse structural biology approaches including cryo-electron microscopy and X-ray crystallography. You will be affiliated with the research group of Christian Löw at EMBL Hamburg located at the recently established Centre for Structural Systems Biology (CSSB) on DESY campus in Hamburg, and work in a close collaborative project with the groups of Jan Kosinski (EMBL Hamburg), Michael Filarsky (University of Hamburg), the cryo-EM Multi-user facility and the protein production team at CSSB. The Löw laboratory is specialized in structural biology of integral membrane proteins and uses innovative approaches to study their structure, function and dynamics.

Your role

You will work in a team of structural and computational biologists at CSSB and investigate endogenous membrane protein complexes in the transmissible gametocyte stages of the malaria parasite Plasmodium falciparum. You will design, perform and troubleshoot experiments in an independent manner, and lead your own research project. The work aims at biological discoveries comprising both methodological and applied aspects.

Apply now

Closing date: 16 January 2022

You have

  • A Ph.D. degree in biochemistry, biophysics or structural biology (or a related field)
  • Experience in structure determination of proteins and protein complexes by cryo-EM
  • Working experience in molecular biology and protein biochemistry with a demonstrated record of accomplishments
  • Ability to plan and pursue a research project independently and in a team
  • Willingness to learn new skills as projects require
  • Excellent communication, interpersonal and English language skills

 

You might also have

  • Experience in other structural biology methods (X-ray crystallography, SAXS, NMR, …)
  • Experimental expertise in the field of membrane proteins
  • Familiarity with eukaryotic expression systems

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family.

Scientists and engineers at the EMBL Hamburg Unit benefit from cutting-edge technology to enable leading research in Structural Biology using on-site synchrotron radiation beamlines operated by EMBL Hamburg and opportunities for collaboration with colleagues from all six EMBL sites.

 

What else you need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with approximately 2000 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research.

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

 

Software Engineer

 


The Protein Function development team is a very dynamic and interdisciplinary team comprising talented and enthusiastic software engineers, bioinformaticians and scientists.  It develops the world leading Universal Protein Resource (UniProt), the Gene Ontology Annotation and Enzyme resources. The UniProt resource is one of the most internationally used protein databases serving a large and diverse research community in genomics, proteins and proteomics.

Proteins are the building blocks of life and knowing how they function in the cells of living organisms gives us an insight on their health and disease states. A Proteome is the set of proteins encoded by the genome of a certain organism. With knowledge in biology generated at an unprecedented accelerating pace, the number of protein sequences in the database has increased dramatically and computational approaches are needed more than ever for organising the protein space for all these organisms.

Your role

In this role you will analyse data, develop production software, create technical documents, take part in the daily Scrum meeting, as well as communicate with other teams at EMBL-EBI and/or with our international collaboration partners. Scalability will be an important feature of your clear, concise, well tested and documented code. You will also be interested in applying analytic engines and technical approaches to distributed processing of big data. The ability to work towards tight deadlines is essential.

We are looking for a Software engineer with a strong record in software development and interested in solving scientific questions related to Big data in biology. The successful candidate will be working in the organization of large data sets of proteins for thousands of organisms in the database. This is a challenging and central development which requires mathematical and statistical expertise as well as strong software development skills. 

Responsibilities include:

  • Design, development, test, document and maintenance of software for the proteomes production pipeline
  • Assist with the data analysis and data processing algorithms 
  • Support and maintain the resource production and service release
  • Engage and coordinate work with different teams in the organization
  • Assist with innovative programming and big data technologies
  • Assist with programming standards to promote best practices

Apply now

Closing date: 20 January 2022

You have

  • A degree in Computer Science, Mathematics, Life Sciences or a related discipline 
  • At least 2 years of working experience in software using Java 
  • Excellent communication skills
  • Ability to work in a team-orientated environment
  • Familiarity with SQL and relational database design principles, Unix shell scripting 
  • Understanding of good coding practices and approaches (OOP, IoC, automated testing, clean code principles, code review) 
  • Familiar with standard development tools (continuous integration e.g. Jenkins, build management e.g. Maven, and source code management systems e.g. GIT, etc).

You might also have

  • Good understanding of Statistics, Graph theory, Probability theory
  • Experience working in bioinformatics and biological resource development would be an advantage

Why join us

Do something meaningful
At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity.

Join a culture of innovation
We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential. 

Enjoy lots of benefits:

  • Financial incentives: Monthly family, child and non-resident allowances, annual salary review, pension scheme including 17% employer contribution, death benefit, long-term care, accident-at-work and unemployment insurances
  • Flexible working arrangements
  • Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover)
  • Generous time off: 30 days annual leave per year, in addition to eight bank holidays
  • Relocation package including installation grant (if required)
  • Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely)
  • Family benefits: On-site nursery, 10 days of child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances
  • Benefits for non-UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance.

For more details please see our employee benefits page.

Image of EMBL-EBI staff member at her desk
"Since my first day at EMBL-EBI, I have cherished how friendly, helpful and talented everyone is. I particularly like the lively exchange of knowledge on campus."
Anja Thormann, Software Developer, Variation team

What else you need to know

  • Contract duration: This position is a 3 year contract
  • International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants
  • Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities. 
  • Job location: This role is based in Hinxton, near Cambridge, UK. You will be required to relocate if you are based overseas and you will receive a generous relocation package to support you.
  • How to apply: To apply please submit a cover letter and a CV through our online system

Bioinformatician


 Are you creative, curious, and ambitious and like to tackle challenging biological data analysis problems?


We have an exciting opportunity for a bioinformatician interested in structural biological data and functional annotations to work within the Protein Data Bank in Europe Team (PDBe) at the European Bioinformatics Institute (EMBL-EBI). In this role, you will integrate proteomics data from PRIDE data resource and structure information in the PDBe. You will also standardize post translational modification data in the PDB archive and update the PDBe and PDBe-KB data resources. 

The Protein Data Bank in Europe Team (PDBe; pdbe.org) is part of the worldwide Protein Data Bank organisation (wwPDB; wwpdb.org), which maintains the global archive of structural data on biomacromolecules - the PDB. The PDBe Team also maintains several databases that support deposition and advanced search services for structural biologists and the wider scientific community. PDBe team also maintains PDBe Knowledge Base (PDBe-KB) of functional annotations for PDB data and is involved in the development of the AlphaFold Protein Structure Database. You will be joining a team consisting of an international and inter-disciplinary mix of professionals including scientists, software engineers, and database engineers.

Your role

This is a scientific, technical role, reporting to the PDBe team leader. You will work on standardising post translational modification information within the PDB archive in collaboration with wwPDB partners. You will also work to update the PDBe and PDBe-KB web pages to display post-translational and proteomics data. Finally, you will also work to update the wwPDB deposition system to provide transparent mechanism to deposit cross-linking data to PRIDE data resource during structure deposition. 

Apply now

Closing date: 26 January 2022

You have

We are looking for a scientific programmer/bioinformatician with strong structural biology background and software engineering skills. You should be able to work both independently and in close collaboration with the PDBe team members. Excellent communication and interpersonal skills, as well as excellent knowledge of English, are therefore required.

You should hold a PhD in Structural biology, Bioinformatics or a related field and a minimum of 2 years of work experience in Structural biology, Bioinformatics or related subjects. Strong knowledge of structural biology and excellent knowledge of Python and API frameworks is expected.

You should have:

  • A proven track record of data analysis using Python libraries
  • Experience in data visualisation
  • Proficiency in Python3+
  • Knowledge of standard data science procedures
  • Experience with programmatic access frameworks (e.g. FastAPI)

You might also have

It is an advantage if you have:

  • Experience in full-stack web development
  • Scientific publications on the field of protein/nucleic acid annotations
  • Experience with Apache Spark
  • Knowledge of front-end development with experience in HTML5, CSS3, JS/TS
  • Knowledge of and experience with JavaScript libraries (e.g. Angular.js, D3.js)
  • Experience in presenting scientific themes at conferences and/or workshops

Why join us

Do something meaningful
At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity.

Join a culture of innovation
We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential. 

Enjoy lots of benefits:

  • Financial incentives: Monthly family, child and non-resident allowances, annual salary review, pension scheme including 17% employer contribution, death benefit, long-term care, accident-at-work and unemployment insurances
  • Flexible working arrangements
  • Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover)
  • Generous time off: 30 days annual leave per year, in addition to eight bank holidays
  • Relocation package including installation grant (if required)
  • Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely)
  • Family benefits: On-site nursery, 10 days of child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances
  • Benefits for non-UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance.

For more details please see our employee benefits page.

 

Image of EMBL-EBI staff member at her desk
"I often find myself involved with completely new tasks that require me to be dynamic and learn a whole new set of skills. You arrive here with a set of skills and knowledge, but you will probably leave having learned a lot more."
Mateus Patricio, Bioinformatician

What else you need to know

  • Contract duration: This position is a grant/project-limited fixed-term contract foreseen for a duration of 3 years or until  01/01/2025 (whichever is shortest).
  • International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants.
  • Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities.
  • Job location: This role is based in Hinxton, near Cambridge, UK. You will be required to relocate if you are based overseas and you will receive a generous relocation package to support you. 
  • Your application: To apply please submit a cover letter and a CV through our online system. We aim to provide a response within two weeks after the closing date.

Postdoc in AI and machine learning, Neural network generalization properties

 


We are looking for a motivated, independent post-doctoral researcher in AI and machine learning eager to work on the development of new methodologies and theory centered on the generalization properties of neural networks, specifically in the context of transfer learning. You would join a collaborative network at Chalmers with researchers in statistics and machine learning (Prof. Rebecka Jörnsten), mathematical statistics (Prof. Johan Jonasson), information theory (Prof. Giuseppe Durisi) and automatic control (Prof. Balazs Kulscar).

Information about the research project
As a post-doctoral researcher you will join Rebecka Jörnsten’s research group at the Division of Applied Mathematics and Statistics. The research group comprises of 4 PhD students. This position is one of 3 post-doctoral openings in the group. The research group is focused on network modeling, data integration and regularization techniques in high-dimensional statistical modeling and neural networks. In addition to the collaborative network identified above, we also collaborate with several research groups in cancer genomics and bioinformatics.

At Chalmers, you will be part of a large network of junior and senior faculty doing research in AI and machine learning. This position is funded through the Chalmers AI research center (CHAIR) which runs seminar series, theme semesters and connects researchers in academia and industry.

Major responsibilities
The post-doctoral position offers an opportunity to further develop your research profile. The majority of your working time is devoted to your own research. As a post-doctoral researcher, you are expected to work independently and to be able to supervise/co-supervise Master’s and Ph.D. students. The teaching of undergraduate students may also be included to a small extent. The position is meritorious for future research duties within academia as well as industry/the public sector.

Contract terms
Full-time temporary employment. The position is limited to a maximum of two years (1+1).

Qualifications
To qualify for this postdoc position, you must have a doctoral degree in a relevant field; statistics, mathematics, data science, or computational sciences. Previous experience with machine learning and/or artificial intelligence is meritorious. You should also be experienced in programming (Python/R or equivalent languages). 

The position requires sound verbal and written communication skills in English. Swedish is not a requirement but Chalmers offers Swedish courses.

We offer
Chalmers offers a cultivating and inspiring working environment in the coastal city of Gothenburg
Read more about working at Chalmers and our benefits for employees.

Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.

Application procedure
The application should be marked with Ref 20210591 and written in English. The application should be sent electronically and be attached as pdf-files, as below:

CV: (Please name the document as: CV, Surname, Ref. number) including:
• CV, include complete list of publications
• Previous teaching and pedagogical experiences
• Two references that we can contact.

Personal letter: (Please name the document as: Personal letter, Family name, Ref. number)
1-3 pages where you:
• Introduce yourself
• Describe your previous research fields and main research results
• Describe your future goals and future research focus

Other documents:
• Attested copies of completed education, grades and other certificates.

Please use the button at the foot of the page to reach the application form. The files may be compressed (zipped).

Application deadline: 6 February, 2022

For questions, please contact:
Annika Lang, Head of unit, Department of Mathematical Sciences
Email: annika.lang@chalmers.se

Rebecka Jörnsten, Department of Mathematical Sciences
Email: jornsten@chalmers.se

*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 
   


The Department of Mathematical Sciences at the Chalmers University of Technology and the University of Gothenburg has about 170 employees and is the largest department of mathematics in Sweden. The department conducts successful research in pure and applied mathematics and mathematical statistics in a wide range of research areas. We are located in a modern building at the center of the Chalmers Johanneberg campus. More information about us can be found on our website.

Chalmers University of Technology conducts research and education in engineering sciences, architecture, technology-related mathematical sciences, natural and nautical sciences, working in close collaboration with industry and society. The strategy for scientific excellence focuses on our six Areas of Advance; Energy, Health Engineering, Information and Communication Technology, Materials Science, Production and Transport. The aim is to make an active contribution to a sustainable future using the basic sciences as a foundation and innovation and entrepreneurship as the central driving forces. Chalmers has around 11,000 students and 3,000 employees. New knowledge and improved technology have characterised Chalmers since its foundation in 1829, completely in accordance with the will of William Chalmers and his motto: Avancez!    


 

Apply

PhD position in cybersecurity for systems

 


With more systems becoming networked, cybersecurity is growing to be increasingly important. There are many different aspects of cyber-security, and for this position we focus on special environments, such as IoT devices, the connected vehicles, and systems with societal importance. The work includes investigation and evaluation of security mechanisms such as intrusion detection systems and how to create resilient designs and architectures, i.e. systems that not only detect deviations from normal behavior but also would be able to report more specifically what is wrong and use additional information to mitigate potential problems and continue to work. 

Information about the department
The Department of Computer Science and Engineering is a joint department at Chalmers University of Technology and the University of Gothenburg, with activities on two campuses in the city of Gothenburg. The department has around 270 employees from over 30 countries.
Our research has a wide span, from theoretical foundations to applied systems development. We provide high quality education at Bachelor's, Master's and graduate levels, offering over 120 courses each year. We also have extensive national and international collaborations with academia, industry and society.

Major responsibilities
Your main responsibility as a PhD student is to pursue your doctoral studies within the framework of the outlined research project. You will be enrolled in a graduate program in the Department of Computer Science and Engineering. You are expected to develop your own ideas and communicate scientific results orally as well as in written form. In addition, the position includes 20% departmental work, mostly as a teaching assistant in Chalmers' undergraduate and masters-level courses or performing other departmental tasks. You will work closely with supervisors in security for system design and development, followed by empirical evaluation to be submitted to academic conferences and journals.

The exact work tasks can be adopted to you and your profile, but research questions can span from system-oriented approaches in understanding under what conditions information is collected and if this collection can be made richer, to algorithmic questions with inspirations from explainable AI to involve investigating transparent and understandable white box mechanisms that complement the expert rather than black-box stand-alone systems.

Contract terms
Full-time temporary employment. The position is limited to a maximum of 5 years. During this time you are expected to obtain a PhD degree. This encompasses 20% departmental duties (typically teaching), 20% studies for credits towards your PhD and 60% research.

Qualifications
To qualify for this PhD student position you must have a master's level degree corresponding to at least 240 higher education credits in Computer Science or Computer Engineering or in a related field, with a good foundation in computer architecture. As a person, you are empathetic, loyal and have high ethical standards. You are also highly motivated, energetic, independent and have the ability to find solutions to complex problems.

Since the research work involves hardware design and development of simulation models, good hardware design and programming skills are required. It is meritorious if you have taken courses in operating systems and compilers.

The position requires sound verbal and written communication skills in English. Swedish is not a requirement but Chalmers offers Swedish courses.

We offer
Chalmers offers a cultivating and inspiring working environment in the coastal city of Gothenburg
Read more about working at Chalmers and our benefits for employees.

Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.

Application procedure
The application should be marked with Ref 20210610 and written in English. The application should be sent electronically and be attached as pdf-files, as below:

CV: (Please name the document: CV, Family name, Ref. number)
• CV
• Other, for example previous employments or leadership qualifications and positions of trust.
• Two references that we can contact.

Personal letter: (Please name the document as: Personal letter, Family name, Ref. number)
1-3 pages where you:
• Introduce yourself
• Describe your previous experience of relevance for the position (e.g. education, thesis work and, if applicable, any other research activities)
• Describe your future goals and future research focus

Other documents:
• Copies of bachelor and/or master’s thesis.
• Attested copies and transcripts of completed education, grades and other certificates, e.g. TOEFL test results.

Please use the button at the foot of the page to reach the application form. The files may be compressed (zipped).

Application deadline: 13 February, 2022

For questions, please contact:
Magnus Almgren, Networks and Systems
Email: magnus.almgren@chalmers.se 
Phone: +46-31-772-11111111

Tomas Olovsson, Networks and Systems
Email: tomas.olovsson@chalmers.se
Phone: +46-31-772-1688

*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 
   



Chalmers University of Technology conducts research and education in engineering sciences, architecture, technology-related mathematical sciences, natural and nautical sciences, working in close collaboration with industry and society. The strategy for scientific excellence focuses on our six Areas of Advance; Energy, Health Engineering, Information and Communication Technology, Materials Science, Production and Transport. The aim is to make an active contribution to a sustainable future using the basic sciences as a foundation and innovation and entrepreneurship as the central driving forces. Chalmers has around 11,000 students and 3,000 employees. New knowledge and improved technology have characterised Chalmers since its foundation in 1829, completely in accordance with the will of William Chalmers and his motto: Avancez!

 


 

Apply

Postdoc in Microbial Robustness

 


Two PhD-students and an experienced researcher is working in the research program on microbial robustness that is funded by the Novo Nordisk Foundation. We are looking for a post doc to extend the team. The overarching goal of the research program is to achieve a molecular understanding of microbial robustness and convert that knowledge to meet the urgent need of efficient industrial catalysts. We want to leverage emerging biotechnologies to put new light on how one can understand microbial robustness by establishing new approaches of experimental and theoretical work.

Here, using yeast as the microbial platform, the natural and industrially exhibited yeast diversity and differently laboratory evolved strains that display different performance and fitness will be taken as a starting point for identifying molecular traits behind microbial robustness. Methodologies that can build a foundation towards understanding microbial robustness under different physiological conditions, will be combined, including genomics, single cell RNA seq, measurements of stress markers, cellular protectants, redox and energy status.

Information about the division
The post doc position is placed at the Division of Industrial Biotechnology within the Department of Biology and Biological Engineering at Chalmers University of Technology. The Industrial Biotechnology group is a young, dynamic and international group of researchers established in 2008 and counts now around 40 members. The common denominator of the research activities in the group is to optimize the use of renewable raw materials for the sustainable production of fuels, chemicals and materials within the main concept of biorefinery.

The research performed within the group spans from fundamental research, technology development and lab-scale application: this ensures deep knowledge of the studied systems, leading to rational development and optimization of the respective applications. The research fields include production of biofuels, chemicals and material via fermentation and enzymatic refining of biomass and bio electrochemical systems. We discover, engineer and apply enzymes and microorganisms. The division has an extensive instrument platform for analytics, molecular biology, protein production and purification, fermentation which are all available for the project. In addition, core facilities with advanced equipment are available within both the Department and at the University campus.

Major responsibilities
The post doc we will recruit will have the challenging task of building understanding of the role of heterogeneity in fermentation processes and cellular strategies coping with perturbations from the environment. We are looking for a post doc that are dedicated to develop cutting-edge methodology for microbial robustness studies and who can put acquired data into a theoretical framework.

Qualifications
You should have a PhD in Systems Biology or Biotechnology/Bioengineering, or related disciplines. Strong foundation in Systems biology, bioinformatics and understanding of yeast physiology is necessary. Extensive hands-on experience with collection and analysis of large omic data sets. Experience in genome editing and studies on single cell level is mandatory experiences and skills. Insights into industrial fermentation processes and experience in fermentation technology and strain engineering is considered a merit.

You need to be self-motivated, ambitious, enthusiastic, creative, well-organised and have good technical abilities. You should be able to put up new experimental procedures and be good in finding new solutions to technical problems. Excellent problem-solving skills, collaborative and social abilities are highly important. You should have strong analytical skills, and a keen interest in the interpretation of complex data. Ability to work in teams and a drive for own development is also important. Good communication skills in English are necessary.

Contract terms
Full-time temporary employment. The position is limited to a maximum of two years (1+1).

We offer
Chalmers offers a cultivating and inspiring working environment in the coastal city of Gothenburg
Read more about working at Chalmers and our benefits for employees.

Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.

Application procedure
The application should be marked with Ref 20210609 and written in English. The application should be sent electronically and be attached as pdf-files, as below:

CV: (Please name the document as: CV, Surname, Ref. number) including:
• CV, include complete list of publications
• Previous teaching and pedagogical experiences
• Two references that we can contact.

Personal letter: (Please name the document as: Personal letter, Family name, Ref. number)
1-3 pages where you:
• Introduce yourself
• Describe your previous research fields and main research results
• Describe your future goals and future research focus

Other documents:
• Attested copies of completed education, grades and other certificates.

Please use the button at the foot of the page to reach the application form. The files may be compressed (zipped).

Application deadline: 15 February, 2022. Applications will be evaluated continuously after 21 January, 2022.

For questions, please contact:
Professor Lisbeth Olsson, Dept. of Biology and Biological Engineering - Industrial Biotechnology
E-mail: lisbeth.olsson@chalmers.se  

*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 
   



Chalmers University of Technology conducts research and education in engineering sciences, architecture, technology-related mathematical sciences, natural and nautical sciences, working in close collaboration with industry and society. The strategy for scientific excellence focuses on our six Areas of Advance; Energy, Health Engineering, Information and Communication Technology, Materials Science, Production and Transport. The aim is to make an active contribution to a sustainable future using the basic sciences as a foundation and innovation and entrepreneurship as the central driving forces. Chalmers has around 11,000 students and 3,000 employees. New knowledge and improved technology have characterised Chalmers since its foundation in 1829, completely in accordance with the will of William Chalmers and his motto: Avancez!    


 

Apply

Postdoc in Synthetic biology of probiotic yeast

 


Focus in this project will be on understanding the production of probiotic yeast with high quality performance. The overall goal for the project is to define the relation between cultivation conditions and cellular quality at single-cell resolution and apply the short-term adaptation principle to produce probiotic yeast of high and consistent quality. Furthermore, in the project relevant model systems to evaluate cell quality in relation to probiotic and pharmaceutical use will be defined. Based on data from RNA-sequencing on population and single-cell level we will elucidate molecular mechanisms and the distribution of subpopulations and potential influence on the probiotic and pharmaceutical functionality.

As a post doc you will work closely with our microbial robustness team, where several PhD-students and post docs are working. The overarching goal of the research program is to achieve a molecular understanding of microbial robustness and convert that knowledge to meet the urgent need of efficient industrial catalysts. We want to leverage emerging biotechnologies to put new light on how one can understand microbial robustness by establishing new approaches of experimental and theoretical work.

Information about the division
The post doc position is placed at the Division of Industrial Biotechnology within the Department of Biology and Biological Engineering at Chalmers University of Technology. The Industrial Biotechnology group is a young, dynamic and international group of researchers established in 2008 and counts now around 40 members. The common denominator of the research activities in the division is to optimize the use of renewable raw materials for the sustainable production of fuels, chemicals, materials and other products.

The research performed within the group spans from fundamental research, technology development and lab-scale application: this ensures deep knowledge of the studied systems, leading to rational development and optimization of the respective applications. We discover, engineer and apply enzymes and microorganisms. The division has an extensive instrument platform for analytics, molecular biology, protein production and purification, fermentation which are all available for the project. In addition, core facilities with advanced equipment are available within both the Department and at the University campus.

Major responsibilities
The post doc we will recruit will have the challenging task of building understanding of the role of heterogeneity in fermentation processes and cellular strategies coping with perturbations from the environment. We are looking for a post doc that are dedicated to develop cutting-edge methodology for the project and who can put acquired data into a theoretical framework.

Qualifications
You should have a PhD in Systems Biology or Biotechnology/Bioengineering, or related disciplines. Strong foundation in Systems biology, bioinformatics and understanding of yeast physiology is necessary. Extensive hands-on experience with collection and analysis of large omic data sets. Experience in genome editing and studies on single cell level is mandatory experiences and skills. Insights into probiotics and evaluation of probiotic potential is considered a merit.

You need to be self-motivated, ambitious, enthusiastic, creative, well-organised and have good technical abilities. You should be able to put up new experimental procedures and be good in finding new solutions to technical problems. Excellent problem-solving skills, collaborative and social abilities are highly important. You should have strong analytical skills, and a keen interest in the interpretation of complex data.  Ability to work in teams and a drive for own development is also important. Good communication skills in English are necessary.

Contract terms
Full-time temporary employment. The position is limited to a maximum of two years (1+1).

We offer
Chalmers offers a cultivating and inspiring working environment in the coastal city of Gothenburg
Read more about working at Chalmers and our benefits for employees.

Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.

Application procedure
The application should be marked with Ref 20210617 and written in English. The application should be sent electronically and be attached as pdf-files, as below:

CV: (Please name the document as: CV, Surname, Ref. number) including:
• CV, include complete list of publications
• Previous teaching and pedagogical experiences
• Two references that we can contact.

Personal letter: (Please name the document as: Personal letter, Family name, Ref. number)
1-3 pages where you:
• Introduce yourself
• Describe your previous research fields and main research results
• Describe your future goals and future research focus

Other documents:
• Attested copies of completed education, grades and other certificates.

Please use the button at the foot of the page to reach the application form. The files may be compressed (zipped).

Application deadline: 15 February, 2022. Applications will be evaluated continuously after 21 January, 2022.

For questions, please contact:
Professor Lisbeth Olsson, Dept. of Biology and Biological Engineering - Industrial Biotechnology
E-mail: lisbeth.olsson@chalmers.se  

*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 
   



Chalmers University of Technology conducts research and education in engineering sciences, architecture, technology-related mathematical sciences, natural and nautical sciences, working in close collaboration with industry and society. The strategy for scientific excellence focuses on our six Areas of Advance; Energy, Health Engineering, Information and Communication Technology, Materials Science, Production and Transport. The aim is to make an active contribution to a sustainable future using the basic sciences as a foundation and innovation and entrepreneurship as the central driving forces. Chalmers has around 11,000 students and 3,000 employees. New knowledge and improved technology have characterised Chalmers since its foundation in 1829, completely in accordance with the will of William Chalmers and his motto: Avancez!    


 

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