Technician Mass Spectrometry

 

The Analytical Biochemistry (AB) group is looking for an experienced technician in the field of analytical chemistry and which is particularly acquainted with mass spectrometry (MS). The AB research group is part of the Groningen Research Institute of Pharmacy (GRIP) and is a dynamic, multidisciplinary group of researchers stemming from the fields of (computational) MS, proteomics and metabolomics. AB is housed in the ERIBA building at the UMCG campus and embeds the Interfaculty Mass Spectrometry Center (IMSC), which is a joint research facility of GRIP and UMCG. AB and IMSC share a well-equipped laboratory with 15 high-end mass spectrometers, primarily hyphenated with LC platforms. There is a well-equipped research infrastructure in place to perform MS-based proteomics and metabolomics, including sample preparation, handling and the analysis of MS data. AB participates in many interdisciplinary research projects, ranging from a fundamental towards a clinical perspective, with a specific focus on biomarker discovery and validation. The AB has workflows in place to enable the analysis of various omics fields such as proteomics, phosphoproteomics, lipidomics and metabolomics and investigating a wide variety of samples such as different types of cancer tissue, lung tissue, microbiological samples, blood and urine.

The technician will be employed at AB under supervision of Prof. Peter Horvatovich and will support the work of principal investigators (PI) Dr Guinevere Langeveen-Kammeijer performing research in glycoproteomics and single cell proteomics, and a new PI to be hired on the subject of mass spectrometry imaging (MSI). Furthermore, the technician will support research activities, infrastructure maintenance and contribute to method development at the IMSC directed by Dr Hjalmar Permentier.

Key responsibilities

• contribution to the development, implementation and validation of new sample preparation methods for single cell proteomics, glycoproteomics, phosphoproteomics and MSI
• performing LC-MS and MSI analyses as well as supporting the reporting of the results
• contributing to the training of Bachelor, Master and PhD students as well as postdoctoral researchers in MS analysis
• maintaining LC-MS and MSI instruments and solving technical problems
• contributing to the overall organization of the AB and IMSC laboratory infrastructure.

Qualifications

• a Bachelor’s or Master’s degree in the area of analytical chemistry or a related field
• demonstrable experience with the operation and maintenance of LC-MS and/or MSI equipment and with LC-MS and/or MSI method development
• good command of oral and written English
• independent, flexible, enterprising, organized, solution-oriented
• affinity with both instrumental techniques and data analysis software
• capable of working in an interdisciplinary, academical, and international environment.

Organisation

The University of Groningen is an internationally oriented university with a rich academic tradition. Since the establishment in 1614, the university has brought forward striving academics, like the first female student, the first Dutch astronaut and various Nobel Prize winners.

Conditions of employment

We offer you in accordance with the Collective Labour Agreement for Dutch Universities:

• depending on level of education and experience of the candidate, the University of Groningen offers a salary between € 2,471 and € 4,257 gross per month (salary scale 7, 8 of 9 according to the collective labour agreements of the Dutch Universities), for a full-time position (1.0 FTE)
• excluding 8% holiday allowance and 8.3% end-of-year bonus over the gross yearly income
• an appointment for a period of one year, but upon proven suitability for the position, based on a positive assessment after one year, there are prospects of an employment contract for an indefinite period.

Application

Please send your application to us, by submitting the following documents:

• letter of application
• curriculum vitae.

You may apply for this position until 14 November 11:59pm / before 15 November 2022 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/(...)rsity-and-inclusion/

Our selection procedure follows the guidelines of the Recruitment code (NVP): https://www.nvp-hrnetwerk.nl/sollicitatiecode/

Unsolicited marketing is not appreciated.

Information

For information you can contact:

• Prof. P.H. Horvatovich, +31 6 31921042, p.l.horvatovich@rug.nl
• Dr H.P. Permentier, +31 6 31921047, h.p.permentier@rug.nl

Please do not use the e-mail address(es) above for applications.

Additional information

• University of Groningen
• The city of Groningen

Apply

PhD position Finding Molecular Glyco(proteo)mic Signatures by Mass Spectrometry

 

The University of Groningen provides a fully funded PhD scholarship in the field of mass spectrometry in the research group of Dr Guinevere Lageveen-Kammeijer. The position is based at the Analytical Biochemistry group, embedded in the Groningen Research Institute of Pharmacy (GRIP) and is a dynamic multidisciplinary group of researchers stemming from the fields of (computational) MS, proteomics and metabolomics.

This PhD project aims to develop the urgently needed analytical tools to decipher and characterize the malignant sugarcode of tumor cells using minimal sample amounts (e.g. single cell analysis). For this purpose, the candidate will develop new sample preparation strategies as well as optimize high-end analytical platforms (nano-liquid chromatography and capillary electrophoresis hyphenated with state-of-the-art mass spectrometers). It is expected that numerous glycomic and glycoproteomic profiles will be generated from various biological samples (e.g. tissues, blood and urine), which will require the development of new data analysis strategies. The obtained information will be used to find glycomic alterations in the field of oncology, which eventually could be exploited for personalized treatment strategies, such as patient diagnosis, prognosis and treatment purposes together with internal and external collaborators. The candidate will be expected to present their work in scientific journals and at scientific conferences.

The PhD project will be executed at the Analytical Biochemistry (AB) group. The AB consists of a dynamic, multidisciplinary group of researchers stemming from the fields of (computational) MS, proteomics and metabolomics. AB is housed in the ERIBA building at the UMCG campus and embeds the Interfaculty Mass Spectrometry Center (IMSC), which is a joint research facility of GRIP and UMCG. AB and IMSC share a well-equipped laboratory with 15 high-end mass spectrometers, primarily hyphenated with LC platforms. There is a well-equipped research infrastructure in place to perform MS-based proteomics and metabolomics, including sample preparation and handling and the analysis of MS data. AB participates in many interdisciplinary research projects, ranging from a fundamental towards a clinical perspective, with a specific focus on biomarker discovery and validation. The AB has workflows in place to enable the analysis of various omics fields such as proteomics, phosphoproteomics, lipidomics and metabolomics and investigating a wide variety of samples such as different types of cancer tissue, lung tissue, microbiological samples, blood and urine.

The PhD position will be supervised by Dr Guinevere S.M. Lageveen-Kammeijer and Prof. Peter L. Horvatovich.

Qualifications

For this position, we seek a highly motivated researcher with practical lab experience in the field of analytical chemistry and data analysis (or another related field). You will be responsible for your own project as well as working within a team. You will be able to manage state-of-the-art mass spectrometers and the corresponding separation platforms.

We are specifically looking for the following:

• hands-on experience with mass spectrometers, liquid chromatography or capillary electrophoresis
• affinity with both instrumental techniques and data analysis software
• MSc degree (GPA> 3.0) in Chemistry, Biochemistry or a related subject
• experience in glyco(proteo)mics is appreciated
• proficiency in English (C1 or higher)
• independent, flexible, enterprising, organized, solution-oriented
• capable of working in an interdisciplinary, academical, and international environment.

Recent illustrative work:

1. Lageveen-Kammeijer, G.S.M.*, Haan, de N.*, Mohaupt, P., Wagt, A.P., Filius, M., Nouta, J., Falck, D., Wuhrer, M. Highly Sensitive CE-ESI-MS Analysis of N-Glycans from Complex Biological Samples. Nature Communications, 2019, 10, 2137, DOI: 10.25345/C5061Z.
2. Wagt, S.*, Haan, de N.*, Wang, W., Zhang, T., Wuhrer, M., Lageveen-Kammeijer, G.S.M. N-glycan isomer differentiation by zero flow capillary electrophoresis coupled to mass spectrometry. Analytical Chemistry, 2022, DOI: 10.1021/acs.analchem.2c02840. Just accepted.
3. Kammeijer, G.S.M., Jansen, B.C., Kohler, I., Heemskerk, A.A.M., Mayboroda, O.A., Hensbergen, P.J., Schappler, J., Wuhrer, M. Sialic Acid Linkage Differentiation of Glycopeptides using Capillary Electrophoresis – Electrospray Ionization – Mass Spectrometry. Scientific Reports, 2017, 7, 3733, DOI: 10.1038/s41598-017-03838-y.
4. Kammeijer, G.S.M., Kohler, I., Jansen, B.C., Hensbergen, P.J., Mayboroda, O.A., Falck, D. Wuhrer, M. Dopant Enriched Nitrogen Gas Combined with Sheathless Capillary Electrophoresis – Electrospray Ionization - Mass Spectrometry for Improved Sensitivity and Repeatability in Glycopeptide Analysis. Analytical Chemistry, 2016, 88 (11), pp 5849-5856, DOI: 10.1021/acs. analchem.6b00479.
5. Madunić, K., Zhang, T., Mayboroda, O.A., Holst, S., Stavenhagen, K., Jin, Chunsheng, Karlsson, N.G., Lageveen-Kammeijer, G.S.M., Wuhrer, M. Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype. Cellular and Molecular Life Sciences, 2021, 78, pp 337-350, DOI: 10.1007/s00018-020-03504-z.

Organisation

The University of Groningen is an internationally oriented university with a rich academic tradition. Since the establishment in 1614, the university has brought forward striving academics, like the first female student, the first Dutch astronaut and various Nobel prize winners.

Conditions of employment

We offer you in accordance with the Collective Labour Agreement for Dutch Universities:

• depending on level of education and experience of the candidate, the University of Groningen offers a salary between € 2,541 and € 3,247 gross per month (scale P according to the collective labour agreements of the Dutch Universities), for a full-time position (1.0 FTE)
• excluding 8% holiday allowance and 8.3% end-of-year bonus over the gross yearly income
• a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that a successful completion of the PhD thesis within the next three years is to be expected.

Application

Please send your application to us, by submitting the following documents:

• letter of application
• curriculum vitae.

You may apply for this position until 15 January 11:59pm / before 16 January 2023 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/(...)rsity-and-inclusion/

Our selection procedure follows the guidelines of the Recruitment code (NVP): https://www.nvp-hrnetwerk.nl/sollicitatiecode/ and European Commission's European Code of Conduct for recruitment of researchers: https://euraxess.ec.europa.eu/jobs/charter/code

Unsolicited marketing is not appreciated.

Information

For information you can contact:

• Prof. P.H. Horvatovich, +31 6 31921042, p.l.horvatovich@rug.nl
• Dr G.S.M. Lageveen-Kammeijer, g.s.m.kammeijer@rug.nl

Please do not use the e-mail address(es) above for applications.

Additional information

• University of Groningen
• The city of Groningen

Apply

PhD position Dynamics of 3D-printed polymer metamaterials

 

We are looking for a PhD candidate to develop, manufacture, and test elastic metamaterials with unusual dynamic properties that can be produced from polymers by additive manufacturing techniques and possess desired (practically advantageous) material behavior (e.g., reduced brittleness, controllable viscosity, improved flexibility, etc.).

Elastic metamaterials extend traditional limits on material and mechanical behavior by tailoring the geometry and arrangement of constituent building blocks. Recent designs of the metamaterials reveal counterintuitive properties such as auxetic behavior (expanding when stretched), energy focusing (lensing), and cloaking (making an embedded object unnoticed). Ideally, these and other functionalities are governed solely by the geometry of building blocks (the metamaterial architecture)and are independent of the properties of base materials. In practice, however, the mechanical behavior of base materials can influence and even suppress metamaterial functionalities.

This project aims to uncover the relations between base materials and architecture for additively manufactured polymeric metamaterials. Polymers are ideal ingredients for metamaterials as they exhibit a broad range of material behaviour (from soft to rigid, from lossless to highly dissipative) that can be controlled by mixing polymer constituents or by the production process. Besides, polymers are abundant in additive manufacturing (AM) – a versatile platform to fabricate metamaterials that offers scalability and unique control over the metamaterial composition and configuration.

The two main goals are:

1. to study the effects of additively manufactured polymers on the dynamics in metamaterials.
2. to leverage optimal polymer compositions for manufacturing metamaterials with predicted mechanical characteristics.

The derived material-architecture relationships will be tested experimentally on prototypes produced by commercial additive manufacturing techniques. The results of this project will allow accurately predicting the dynamics of polymeric metamaterials that has been challenging so far and thus will open the potential of metamaterials to real-world applications. The PhD candidate will be supervised by Dr Anastasiia O. Krushynska (CMME group) and Prof. Ranjita Bose (CPE group).

Qualifications

You should have:

• a Master degree in Mechanical Engineering, Material Science, Aerospace Engineering, Civil Engineering, or equivalent disciplines
• skilled experience in computational dynamics or experimental material characterization (preferable)
• knowledge of, or willingness to learn, polymer structure-property relationships
• willingness to explore new research directions and “mechanical intuition” will be a plus.

We are searching for a passionate and enthusiastic student with an interest in the fundamental and applied aspects of research. You will work within a team in a multidisciplinary research environment (Materials Science, Ultrasonics, Polymer Science, Chemical Engineering). Thus, the desire to learn new topics and the ability to communicate research results are of a special importance. In the course of this project, you will develop yourself as a researcher who is able to present cutting-edge research results in high-quality publications and leading international (interdisciplinary) conferences of specialists and to broader audiences. The ability to work in a group and a very good knowledge of English are highly appreciated.

Organisation

Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and creative institution of higher education offering high-quality guiding and research. Flexible study programs and academic career opportunities in a wide variety of disciplines support the 36 000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, we join efforts with other top universities and networks worldwide to become a truly global center of knowledge.

The Computational Mechanical and Materials Engineering (CMME) group of the Engineering and Technology Institute Groningen (ENTEG) is active in various research fields including advanced materials, energy and systems complexity, manufacturing of complex materials. Our research mainly focuses on (meta-) material design, modeling methods and tools, and engineering systems, ranging from the atomistic world up to the scale of mechanical devices and systems of devices. The Chemical Product Engineering (CPE) group aims at performing research for the design of new or improved chemical products. Particular attention is devoted to the development of polymer structure-property relationships for the development of new functional materials and specific applications of polymeric materials. ENTEG seeks at performing excellent research and guiding directed at the integration of fundamental and engineering sciences.

Conditions of employment

We offer you in accordance with the Collective Labour Agreement for Dutch Universities:

• a salary of € 2,541 gross per month in the first year, up to a maximum of € 3,247 gross per month in the fourth and final year
• a holiday allowance of 8% gross annual income
• an 8.3% end-of-the-year allowance
• a temporary fulltime (1.0 FTE) position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that you successfully complete your PhD thesis within the next three years. The position has a duration to a period of 4 years.

A PhD training program is part of the agreement and you will be enrolled in the Graduate School of Science and Engineering.

Application

Do you meet the qualification criteria? If yes, your application should include:

• a letter of motivation (max. 2 pages)
• a curriculum vitae
• a list of publications (if any)
• recommendation letter(s)
• a certification of the English language proficiency.

Please submit your application until 30 November 11:59pm / before 1 December 2022 Dutch local time (CET) by clicking on button “Apply” below and filling in the application form. The interviews will be performed in November-December 2022.

The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/(...)rsity-and-inclusion/

Our selection procedure follows the guidelines of the Recruitment code (NVP): https://www.nvp-hrnetwerk.nl/sollicitatiecode/ and European Commission's European Code of Conduct for recruitment of researchers: https://euraxess.ec.europa.eu/jobs/charter/code

Unsolicited marketing is not appreciated.

Information

For information you can contact:

• Dr A. O. Krushynska (for questions regarding the project), a.o.krushynska@rug.nl
• Mr. F.D. Salverda (for questions regarding the submission procedure), f.d.salverda@rug.nl

Please do not use the e-mail address(es) above for applications.

Apply

PhD in the discovery, characterization and engineering of novel enzymes

 

Applications are invited for a 4-year PhD position in the discovery, characterization and engineering of novel enzymes for biocatalytic applications, starting as soon as possible, in the research group of Dr Sandy Schmidt, (http://schmidt-researchgroup.com) at the Department of Chemical and Pharmaceutical Biology (https://www.rug.nl/research/grip/cpb/) within the Groningen Research Institute of Pharmacy (GRIP).

Biocatalysis uses enzymes to replace traditional catalysts. This technology has already established sustainable enzymatic approaches across various industrial sectors and led to economic and environmental benefits. Despite the growing impact of biocatalysis in industrial chemistry, the full potential of this technology is yet to be unlocked. Important current limitations are the following: i) only a limited set of chemical reactions is amenable to biocatalysis; and ii) the unique enzymology encoded in the genome of organisms is yet only minimally explored.

In this context, we are interested in decoding novel reaction chemistries from enzymes that are not accessible with the existing biocatalyst portfolio. With this, we intend to build important molecules such as precursors for pharmaceuticals. A particular focus thereby lies on enzymes from natural product biosynthetic gene clusters that catalyze unique chemical reactions, but are tremendously underexplored as sustainable biocatalysts in the chemical industry. Although their native reactions have recently been investigated, the lack of knowledge on how these enzymes perform challenging reactions hinders a systematical exploration of their reactivity toward non-natural substrates and transformations.

To fill this knowledge gap, in this PhD project we will extend the diversity of available biocatalysts by a genome mining approach from relevant biosynthetic gene clusters and a bioinformatic analysis (based on sequence-similarity networks and genome neighborhood analysis) along with an in-depth biochemical characterization and elucidation of the substrate and reaction scope to deliver a diverse set of promiscuous enzymes. Eventually, identified promiscuous enzymes will be engineered to further increase the desired reactivities to a practical level.

Qualifications

The ideal candidate for this project is an experimental chemist or biologist, with affinity or interest in computational biology, biocatalysis and protein engineering. Some basic Python knowledge is beneficial, but not a must.

Your profile includes:

• a Master degree in chemistry, biotechnology, (molecular) biology, biochemistry or related field
• ability to work in an international team,
• inter- and multidisciplinary thinking,
• high motivation,
• an integrative and cooperative personality with excellent communication and social skills,
• fluency in English – written and oral.

Organisation

Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 36,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge. The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines. Our community has an open and informal character with students and staff from around the world.

The research group Chemical and Pharmaceutical Biology (CPB) within GRIP consists of an enthusiastic group of researchers from different parts of the world.

The scientific staff currently includes two full professors, one associate professor, and two assistant professors. In addition, two postdocs, four technicians and >25 PhD students are members of the research group. A strong research focus of CPB is on the creation of superior biocatalysts for the sustainable production of pharmaceuticals.

Conditions of employment

We offer you, in accordance with the Collective Labour Agreement for Dutch Universities:

• a salary of € 2,541 gross per month in the first year, up to a maximum of € 3,247 gross per month in the fourth and final year
• a holiday allowance of 8% gross annual income
• an 8.3% end-of-year bonus and participation in a pension scheme for employees
• first, a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that a successful completion of the PhD thesis within the next three years is to be expected. A PhD training programme is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering.

The conditions of employment: https://www.rug.nl/about-us/work-with-us/

Application

You may apply until 30 November 11:59pm / before 1 December 2022 Dutch local time (CET) for this position by means of the online application form (click on "Apply" below on the advertisement on the university website).

Applications for the position should include (as a single PDF file):

• cover letter with background and motivation to apply for this position
• curriculum vitae, including details of Bachelor and Master degrees, lab work experience and a publication list, if applicable
• detailed (max. 2 pages) description of previous research experience
• contact details of 2 academic references who can provide information on your suitability for the position.

The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/(...)rsity-and-inclusion/

Our selection procedure follows the guidelines of the Recruitment code (NVP), https://www.nvp-hrnetwerk.nl/sollicitatiecode/ and European Commission's European Code of Conduct for recruitment of researchers, https://euraxess.ec.europa.eu/jobs/charter/code

Unsolicited marketing is not appreciated.

Information

For information you can contact:

• Dr Sandy Schmidt, s.schmidt@rug.nl

Please do not use the e-mail address(es) above for applications.

Additional information

• University of Groningen
• Groningen Research Institute of Pharmacy

Apply

Assistant Professor in Audience Research

 

While the arts have always depended on their audiences and aesthetic experiences, the roles that audiences play have changed. Participatory culture, both offline and online, increasingly blurred lines between amateur producers and professionals, internationalization, as well as calls for increased diversity and improved representation have challenged traditional art institutions and employment models of artists. At the same time, these developments have also opened up new opportunities for a wider spectrum of artists and cultural workers via decolonialization of art institutions, participatory governance models, and generation of new internet-afforded income revenues. To address the contemporary implications of audience activity, and how it affects artists and institutions, we seek a new colleague specialized in audience research.

The candidate we are looking for has:

• excellent skills in research methodologies relevant for studying art experiences and audiences’ perspectives: Conventional qualitative and/or quantitative research methods as well as different methodologies such as practice-based research, community engagement, participatory action research, or digital ethnography
• a demonstrable interest in relating audience research to questions of cultural production processes today
• familiarity with theoretical approaches in sociology of arts and culture as well as some affinity with research on cultural entrepreneurship and cultural policies
• a background in sociology of arts and culture, cultural consumption studies, media studies, cultural studies or an arts discipline (music, theatre, film, visual art, literature).

Courses in which the candidate is expected to be involved: Sociology of the Arts I & II; Empirical Methods: Arts, Policy, and Education; Management and Entrepreneurship in the Arts; Organising and Communicating in the Arts; BA- and MA thesis supervision; and possible involvement in arts-specific or interarts-related courses in the department.

Research is conducted within the Groningen Institute for the Study of Culture (ICOG) (https://www.rug.nl/research/icog/?lang=en) and its Research Centre Arts in Society (https://www.rug.nl/(...)erformance%20studies.). ICOG and the Faculty of Arts provide ample support in applying for bids with national and international funding agencies. There is also an annual travel budget for conference participations and other research-related activities.

Specific tasks

• teach and supervise students in the department’s undergraduate and graduate programmes, specifically in the Arts, Policy and Cultural Entrepreneurship track in the BA program of Arts, Culture and Media and MA programs of Arts & Culture
• participate actively in curriculum development, design and administration of course modules
• generate high-quality research in above mentioned fields
• external grant acquisition
• participate actively in international research networks
• participate in the activities of the interdisciplinary research centre Arts in Society and (one of) its theme groups
• performing administrative and organizational duties.

Qualifications

In addition to a number of basic requirements set by the University of Groningen, such as excellent social and communication skills, presentation skills, coaching skills, a results-oriented attitude, and excellent command of English (at least CEFR B2/C1 level for reading, listening, writing and speaking), we are looking for candidates who have a PhD in one of the above-mentioned fields and, in the area of teaching:

• have relevant teaching experience at a university level; are excellent teachers, as demonstrated by creative, innovative and meaningful approaches to teaching and learning described in the teaching statement
• have gained the University Teaching Qualification or are prepared to do so within a year
• are prepared to foster inclusive learning environments
• are demonstrably able to make concrete contributions to the design and development of course units, partly by actively linking teaching to research.

In the area of research:

• have or are in the process of establishing an excellent international research profile or set up their own innovative research line and have published with internationally recognized journals and publishers
• have success with or the motivation and potential (through documented record of e.g., past applications) to acquire third-party funding on the national or international level (future research plans to be described in the research statement)
• have international experience and a relevant national and international academic network
• are able to supervise students (all BA, MA and PhD levels).

In the area of management and organization:

• have excellent command of English (at least CEFR B2/C1 level for reading, listening, writing and speaking)
• are expected to have or gain understanding of the Dutch language (CEFR B2 for reading and listening, and CEFR B1 for writing and speaking) within two years
• are willing to contribute to the development of the department’s research and educational programmes
• are able to make a constructive contribution to interdisciplinary collaboration and a friendly atmosphere within the department
• have demonstrable administrative, time-management and organization skills.

Organisation

Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Balanced study and career paths in a wide variety of disciplines encourage the 36,000 students and researchers to develop their own individual talents. Belonging to the best research universities in Europe and joining forces with prestigious partner universities and networks, the University of Groningen is truly an international place of knowledge.

Conditions of employment

We offer you in accordance with the Collective Labour Agreement for Dutch Universities:

• a salary, depending on qualifications and work experience, with a minimum of € 3,974 (salary scale 11) to a maximum of € 6,181 (salary scale 12) gross per month for a full-time position a full-time position (1.0 FTE)
• a holiday allowance of 8% gross annual income
• an 8.3% end-of-the-year allowance
• minimum of 29 holidays and additional 12 holidays in case of full-time employment.

The position entails a contract combining 60% teaching tasks with 40% research-time. Favourable tax agreements may apply to non-Dutch applicants. There is a probationary period of 18 months. After a positive assessment at the end of this period the contract will be converted into a permanent one. The candidate is expected to live and work in Groningen for this position.
The conditions of employment comply with the Collective Labour Agreement for Dutch Universities (CAO NU). For more detailed information about working conditions and working for the University of Groningen, please check: https://www.rug.nl/(...)k-with-us/new-staff/

Starting date: 1 September 2023 (or earlier if possible)

Application

You may apply for this position until 30 November 11:59pm / before 1 December 2022 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

Applications (in PDF files) should include:

● a cover letter that explains the motivation for applying for this position
● a full curriculum vitae including a full list of publications, taught courses, external funding, teaching qualification
● a research plan of 1-2 pages that includes future ideas for projects and grant applications
● a teaching statement, in maximum of 2 pages, that outlines your teaching philosophy
● the names and contact details of two academic referees

Only complete applications submitted by the deadline will be taken into consideration.

The selection interviews will take place during the spring of 2023.

The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/(...)rsity-and-inclusion/

Our selection procedure follows the guidelines of the Recruitment code (NVP): https://www.nvp-hrnetwerk.nl/sollicitatiecode/ and European Commission's European Code of Conduct for recruitment of researchers: https://euraxess.ec.europa.eu/jobs/charter/code

We provide career services for partners of new faculty members moving to Groningen.

Unsolicited marketing is not appreciated.

Information

For information you can contact:

• Dr Sara Malou Strandvad, Associate Professor in Arts Sociology (about this position), s.m.strandvad@rug.nl
• Miralda Meulman, Degree programme coordinator (about the formal procedure), sec.amc@rug.nl

Please do not use the e-mail address(es) above for applications.

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Tenure Track Assistant Professor in Genome editing

 

We are looking for an Assistant Professor who can strengthen our position in the field of Genome editing. Central to this discipline is the development of efficient genetic-based strategies to engineer cells. Recent advances in gene editing based on CRISPR/Cas systems have triggered a revolution in gene targeting and genome editing research, with the potential to radically reshape the treatment of genetic diseases by replacing or deleting defective genes. Developments within this discipline are fast and include, but are not limited to, the discovery and design of novel CRISPR/Cas systems with new or improved functions, enabling diverse medical and biotechnological applications. CRISPR/Cas associated technologies have shown immense promise for human gene and cell therapy, diagnosis, construction of animal- and cell-models for disease investigations, and many other applications including genome editing in plants and microbes.

The ultimate objective of the discipline is the development of effective genetic-based strategies to better combat human diseases. The development of procedures for efficient and safe delivery of CRISPR/Cas systems to target cells or tissues remains crucial for application in clinical gene therapy. The development of CRISPR/Cas-based systems as advanced tools to detect the presence of viral pathogens or treat viral disease is another possible research area.

As Assistant Professor you will:

• set up and develop your own research line and research group, in the field of Genome editing, for instance in some of the topics mentioned above
• supervise PhD candidates
• acquire external funding
• promote the societal relevance of your research
• teach in and contribute to the development of courses in the Bachelor programs of Pharmacy and Life Sciences and Technology, as well as the Master programs of Pharmacy and Medical Pharmaceutical Sciences
• contribute to the organization of the faculty, for example by participating in working groups and committees, in the domains of teaching, research and management.

At the stage of Assistant Professor 60% of your time is for research, 30% for teaching activities and 10% for organizational tasks.

Qualifications

We encourage you to apply if you have:

• a PhD degree in genetics, molecular biology, biotechnology, or other related fields
• extensive experience with gene/genome editing using CRISPR-Cas systems
• at least two years of postdoctoral experience outside of the Netherlands, preferably in a different country than where you received your PhD (can be compensated for after the appointment via extended research visits abroad)
• a relevant international network
• excellent research qualities, as shown by a publication record in international peer-reviewed journals and proceedings of renowned conferences
• a good track record in teaching, appropriate to your career stage
• demonstrable organizational competences
• good command of spoken and written English.

And you are:

• a team player with good communication skills
• able to work well in an international, culturally diverse, environment
• able to acquire substantial research grants from external sources
• willing to obtain a University Teaching Qualification (Dutch: BKO) within three years
• able to speak the Dutch language or motivated to speak it within five years.

Organisation

The University of Groningen is a research university with a global outlook, deeply rooted in Groningen, City of Talent. Quality has been our top priority for over four hundred years, and with success: the University is currently in or around the top 100 on several influential ranking lists.

The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines, from classical disciplines such as mathematics, astronomy and mechanical engineering, to interdisciplinary fields such as artificial intelligence, pharmacy and nanoscience. Our community has an open and informal character with students and staff from around the world.

The position we offer will be embedded in the Groningen Research Institute of Pharmacy (GRIP), and specifically in the research group Chemical and Pharmaceutical Biology. Although GRIP is positioned within the Faculty of Science and Engineering, it is physically located within the University Medical Centre Groningen (UMCG) of the Faculty of Medical Sciences - hence, in ideal proximity to benefit from collaborations between the two faculties. Together with Medical Sciences, GRIP participates in the joint UMCG-FSE Research Institute GUIDE (Groningen University Institute for Drug Exploration). Pharmaceutical research within GRIP is highly multidisciplinary. It bridges the clinical and biomedical sciences on the one hand, and chemistry, mathematics (statistics) and physics on the other. The interaction between the pharmaceutical sciences and these fundamental and clinical sciences offers excellent opportunities for ground-breaking research.

Conditions of employment

We offer you a full-time position as Assistant Professor in our faculty’s tenure track system Career Paths in Science and:

● a salary, depending on qualifications and work experience, from € 3,974 up to a maximum of € 6,181 gross per month (scale 11 or 12 CAO Dutch Universities, depending on your career stage) for a full-time position
● holiday allowance and end-of-year bonus of respectively 8% and 8.3% of your yearly salary;
● a pension scheme
● maternity and parental leave
● the possibility to work part-time (0,9 fte or 0,8 fte)
● a mentor program and a broad range of opportunities for personal development
● dual career support for partners of new faculty members moving to Groninge.

Consider our website for more information about the working conditions at the University of Groningen: https://www.rug.nl/(...)with-us/that-is-why/

As Assistant Professor you will enter a tenure track that, if followed successfully, will lead to a Full Professorship in approximately 10 years. In case of a full-time contract, you will initially be appointed for 7 years and your performance will be assessed after 5 years. This moment may be extended with at most one year in case of a life event (e.g. prolonged illness or maternity leave). If your assessment is positive, you will get a tenured appointment as an Associate Professor. After another 4 to 7 years you will be assessed for promotion to the position of Full Professor. Please consider Career Paths in Science for a complete description of our tenure track system as well as the criteria for promotion: https://www.rug.nl/(...)ce-edition-4?lang=en.

Application

We invite you to submit a complete application including:

● a cover letter in which you describe your motivation and qualifications for the position
● a curriculum vitae, including a list of your publications and a list with names of references
● a list of five self-selected ‘best papers’
● a statement of your teaching goals and experience
● a description of your scientific interest and plans.

You may apply for this position until 28 November 11:59pm / before 29 November 2022 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

The selection interviews will take place on 15 December 2022.

The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/(...)rsity-and-inclusion/

Our selection procedure follows the guidelines of the Recruitment code (NVP): https://www.nvp-hrnetwerk.nl/sollicitatiecode/ and European Commission's European Code of Conduct for recruitment of researchers: https://euraxess.ec.europa.eu/jobs/charter/code

We provide career services for partners of new faculty members moving to Groningen.

Unsolicited marketing is not appreciated.

Information

For information you can contact:

• Prof. dr. G.J. Poelarends, +31503638174, g.j.poelarends@rug.nl

Please do not use the e-mail address(es) above for applications.

Additional information

• Profile report in which the position is described in more detail
• More information about the research institute
• More information about the employment conditions of the University of Groninge
• Career Paths in Science

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