At the Faculty of Medicine, Department of Health Science and Technology at Aalborg University invites applications for a position as postdoc in the field statistical genetics of neurodegenerative disorders such as Parkinson’s disease. The applicant is expected to start March 1, 2022 or soon hereafter, and the position is fixed-term full-time position for 23 months.
JOB DESCRIPTION
Department of Health Science and Technology carries out multidisciplinary research, teaching and dissemination within biomedical engineering, sports science and medicine. The department has more than 250 employees and is responsible for more than 1700 students. More than 100 PhD students are enrolled in the doctoral school affiliated to the department. The researchers are organized in a number of research groups and centres, and the department has at its disposal laboratory and clean room facilities for cell growth, molecular biology, brain analysis, 3D movement analysis, respiratory and circulatory examinations, sensory and motor functions analysis, etc. All study programs at Aalborg University involve problem-based learning, organized around cases and projects. For more, see: www.hst.aau.dk.
Using a combination of computational and experimental biology we are searching for genetic variation linked to disease, and for this project we are interested in genetic variation linked to Parkinson’s disease (PD). PD is a common neurological disease affecting millions of people worldwide. To improve the life quality of the patients a deeper understanding of the genetic basis is important. Such information can be used in the future for development of new medicine that can provide relief from symptoms and be tailed to the individual. The purpose of the proposed research project is to study the genetic aetiology underlying PD by exploiting large human cohorts (the UK Biobank and the International Parkinson’s Disease Genomics Consortium) utilising new statistical genetic tools that not only use individual genetic variants, but also leverage prior biological knowledge from different external sources.
Your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality.
Your main tasks will consist of:
- Article Apply for and manage genetic and phenotypic data.
- Identify sources of knowledge (i.e., gene expression, protein interactions, gene-drug interactions, biological networks etc.) for integration in the statistical framework.
- Perform genetic association and burden analyses of common and rare genetic variants.
- Development prediction models (polygenic risk scores).
- Visualize, present, and communicate data in weekly meetings and at international conferences.
Qualification requirements:
You have academic qualifications at PhD level, with expertise in several of the following areas:
- Biostatistics
- Human molecular genetics
- Statistical genetics of complex traits
- Analysis of human common and rare genetic variation
- Big-data experience
- Reproducible science
- Experienced user of UNIX-based high-performance computing (HPC) cluster, R|Python, bash and alike
As a person, you are ambitious, independent, self-motivated, take ownership and possess good communication skills. We expect you to be fluent in oral and written English.
You may obtain further professional information from Professor Mette Nyegaard: nyegaard@hst.aau.dk.
Appointment as Postdoc presupposes scientific qualifications at PhD–level or similar scientific qualifications. The research potential of each applicant will be emphasized in the overall assessment. Appointment as a Postdoc cannot exceed a period of four years in total at Aalborg University.
The application must contain the following:
- A motivated text wherein the reasons for applying, qualifications in relation to the position, and intentions and visions for the position are stated.
- A current curriculum vitae.
- Copies of relevant diplomas (Master of Science and PhD). On request you could be asked for an official English translation.
- Scientific qualifications. A complete list of publications must be attached with an indication of the works the applicant wishes to be considered. You may attach up to 5 publications.
- Dissemination qualifications, including participation on committees or boards, participation in organisations and the like.
- Additional qualifications in relation to the position. References/recommendations.
- Personal data.
The applications are only to be submitted online by using the "Apply online" button below.
Shortlisting will be applied. After the review of any objections regarding the assessment committee, the head of department, with assistance from the chair of the assessment committee, selects the candidates to be assessed. All applicants will be informed as to whether they will advance to assessment or not.
AAU wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background or belief.
For further information concerning the application procedure please contact Jeannette Bøgh by mail Jebo@adm.aau.dk or phone (+45) 9940 7968.
Information regarding guidelines, ministerial circular in force and procedures can be seen here
AGREEMENT
Employment is in accordance with the Ministerial Order on the Appointment of Academic Staff at Universities (the Appointment Order) and the Ministry of Finance's current Job Structure for Academic Staff at Universities. Employment and salary are in accordance with the collective agreement for state-employed academics.
VACANCY NUMBER
2021-224-03906
DEADLINE
15/01/2022
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